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Oocyte Cryopreservation: Who, how and what to Expect | OMICS International | Abstract
ISSN: 2375-4508

Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology
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Editorial

Oocyte Cryopreservation: Who, how and what to Expect

Paolo Emanuele Levi Setti1,2,3*, Marcello Desgro2, Alberto Vaiarelli2 and Pasquale Patrizio3
1IRCCS Istituto Clinico Humanitas, via Manzoni 56, 20089, Rozzano (Milan), Italy
2Department of Gynecology, Division Gynecology and Reproductive Medicine, Istituto Clinico Humanitas IRCCS -University of Milan, School of Medicine - Rozzano(Milan), Italy
3Yale Fertility Center and REI Medical Practice, Yale University, School of Medicine - New Heaven, Connecticut, USA
*Corresponding Author : Paolo Emanuele Levi Setti
IRCCS Istituto Clinico Humanitas
via Manzoni 56, 20089
Rozzano (Milan), Italy
E-mail: [email protected]
Received October 25, 2012; Accepted October 25, 2012; Published October 27, 2012
Citation: Setti PEL, Desgro M, Vaiarelli A, Patrizio P (2012) Oocyte Cryopreservation: Who, how and what to Expect. J Fert In Vitro 2:e118. doi:10.4172/2165-7491.1000e118
Copyright: © 2012 Setti PEL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Oocyte cryopreservation is gaining widespread clinical acceptance. The main indications include: a) Fertility preservation in cancer patients or other fertility-impairing conditions; b) Patients at risk of premature ovarian failure; c) Oocytes banking for donation programs; d) Cases with no sperm available at the time of oocyte harvesting; and e) Cases where for religious reasons patients prefer to cryopreserve gametes instead of embryos. Oocytes cryopreservation has recently been proposed also for women that wish to postpone their reproductive plans at later age for career or social reasons. The utilization of oocyte preservation in this setting is appealing also from an ethical perspective, allowing maintenaince of reproductive autonomy and rights at later age, thus avoiding the stigma of childlessness or resorting to oocytes donation to fullfil the desire of motherhood. However, despite increasing reports about the safety (hundreds of documented births and reassuring data on obstetrical and neonatal safety), the 2009 practice committee opinion of the American Society for Reproductive Medicine (ASRM) still considers oocyte cryopreservation an experimental procedure requiring an investigational IRB-approved protocol. It is anticipated that soon the ASRM by reviewing the accumulating worldwide evidence of high survival and pregnancy rates, comparable to those obtained with fresh oocytes, will remove the label of experimental.

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