alexa Opioid-Induced Cardioprotection against Ischemia-Reperfusion Injury: The Challenge in Diabetes | OMICS International | Abstract
ISSN: 2155-6156

Journal of Diabetes & Metabolism
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Mini Review

Opioid-Induced Cardioprotection against Ischemia-Reperfusion Injury: The Challenge in Diabetes

Shaoqing Lei1,2,3, Wating Su1, Rui Xue1, Huimin Liu1, Liangqing Zhang2, Huilai Miao2, Youtan Liu2, Haobo Li3, Michael G Irwin3 and Zhengyuan Xia2,3*

1Department of Anaesthesiology, Renmin Hospital of Wuhan University, Wuhan, China

2Department of Anesthesiology, Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, China

3Department of Anaesthesiology, the University of Hong kong, Hongkong SAR, China

*Corresponding Author:
Dr. Zhengyuan Xia
Department of Anaesthesiology
The University of Hong Kong, Hong Kong
Tel: 852-3917-9794; 852-3917-9786
Email: [email protected]

Received date: October 01, 2015 Accepted date: October 13, 2015 Published date: October 16, 2015

Citation: Lei S, Su W, Xue R, Liu H, Zhang L, et al. (2015) Opioid-Induced Cardioprotection against Ischemia-Reperfusion Injury: The Challenge in Diabetes. J Diabetes Metab 6:616. doi:10.4172/2155-6156.1000616

Copyright: © 2015 Lei S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Ischemic heart disease is the leading cause of


and mortality in diabetes. Patients with diabetes are particularly at risk of perioperative myocardial infarction, and are less resistant to myocardial ischemia-reperfusion injury (IRI), but the underlying mechanisms are very unclear. Opioid conditioning has been well demonstrated to be protective against myocardial IRI like ischemic conditioning, but this effect is compromised in diabetic condition, and little is known about the role of opioid-induced cardioprotection during diabetes. This brief review is to provide a summary of our present understanding of the effects of diabetes on opioids induced


against myocardial IRI and the challenges of limiting IRI by opioids in the

diabetic heart



Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7