gmo

General Medicine: Open Access

ISSN - 2327-5146

Abstract

A Review on Pharmacological Management of Generalised Tetanus

Bhupendra Shah

Background: Tetanus is a major public concern in the developing world and is still encountered in the developed world. The evidence regarding the management of the tetanus is limited making the protocol based treatment of tetanus an unmet goal especially in low to middle-income countries. This article was our endeavour to review the management of the patient.
Methods: Two authors extensively searched electronic databases like MEDLINE/Pub Med and Google Scholar, searched with Mesh (Medical Subject Headings) terms like “tetanus”, “treatment”, “benzodiazepines”, “ Tetanus immunoglobin” from the earliest possible date of 1966 to January 2018.
Conclusion: We found that diazepam was the drug of choice for controlling muscle spasm, magnesium sulphate controls the autonomic instability, human tetanus immunoglobin bind the unbound toxin, and proper wound care is a must.

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