alexa Paraneoplastic Cerebellar Degeneration: A Rare but Important Consideration
ISSN: 2165-7920

Journal of Clinical Case Reports
Open Access

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Case Report

Paraneoplastic Cerebellar Degeneration: A Rare but Important Consideration

Prithvi Giri1, Rakesh Shukla2*, Vikram V Holla1 and Vinod Kumar Mehta1
1Senior Resident, Department of Neurology, King George’s Medical University, Lucknow, India
2Professor, Department of Neurology, King George’s Medical University, Lucknow, India
*Corresponding Author : Rakesh Shukla
Department of Neurology
King George’s Medical University, Lucknow, India
Tel: 09415007015
E-mail: [email protected]
Received: November 12, 2015; Accepted: January 08, 2016; Published: January 13, 2016
Citation: Giri P, Shukla R, Holla VV, Mehta VK (2016) Paraneoplastic Cerebellar Degeneration: A Rare but Important Consideration. J Clin Case Rep 6:700.doi:10.4172/2165-7920.1000700
Copyright: © 2016 Giri P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Paraneoplastic cerebellar degeneration is an uncommon autoimmune disorder characterized clinically by progressive, ultimately incapacitating ataxia and pathologically by destruction of cerebellar Purkinje cells, with variable loss of other cell populations. The paraneoplastic cerebellar degeneration can antedate the recognition of malignancy and hence can be a warning sign for occult tumor. We are reporting two cases of paraneoplastic cerebellar degeneration that presented before any evidence of tumor and later developed advanced stage of malignancy not amenable for surgery.

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