Partial Exchange Transfusion for Hyperviscosity and Necrotizing Enterocolitis after Complication of Intravenous Immunoglobulin in a Late Preterm Infant: Case Report and Review of the Literature
A Ulas Tugcu*, Ayse Ecevit, Aslihan Abbasoglu, Namik Ozbek and Aylin Tarcan
Baskent University Ankara Hospital Faculty of Medicine, Department of Pediatrics, Division of Neonatology, Ankara, Turkiye
- *Corresponding Author:
- Dr. A. Ulas TUGCU
Baskent University Ankara Hospital
Faculty of Medicine, Department of Pediatrics
Division of Neonatology, Ankara, Turkiye
Tel: +90 312 212 68 68
Fax: +90 312 212 34 94
E-mail: [email protected]
Received Date: May 11, 2013; Accepted Date: June 16, 2013; Published Date: June 26, 2013
Citation: Ulas Tugcu A, Ecevit A, Abbasoglu A, Ozbek N, Tarcan A (2013) Partial Exchange Transfusion for Hyperviscosity and Necrotizing Enterocolitis after Complication of Intravenous Immunoglobulin in a Late Preterm Infant: Case Report and Review of the Literature. Pediat Therapeut 3:156. doi:10.4172/2161-0665.1000156
Copyright: © 2013 Ulas Tugcu A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Thrombocytopenia is not rare haematologic finding in the sick newborn infants, it occurs frequently in patients who were admitted to newborn intensive care units. Use of intravenous immunoglobulin (IVIG) in newborn infants has brought some amelioration to primary and secondary immune deficiencies, haemolytic disease of newborn, autoimmune thrombocytopenias and sepsis. There have been reports of thrombotic events in especially in adults and children after usage of high dose IVIG. However some unexpected adverse effects started to be reported by the increasing usage of IVIG. In this case we described a late preterm infant with necrotizing enterocolitis after IVIG treatment of neonatal isoimmune thrombocytopenia. After IVIG treatment, necrotizing enterocolitis began to occur and high blood viscosity was detected. We performed partially exchange transfusion. Thrombocyte numbers did not increase but significant improvement of clinical status occurred.