Pathological Investigations on Galilee Tilapia (Sarotherodon galilaeus) Following Chronic Exposure to Cadmium Chloride
- *Corresponding Author:
- Ramy M Shourbela
Department of Animal Husbandry and Animal
Wealth Development, (Fish Breeding and Production)
Faculty of Veterinary Medicine, Alexandria University, Egypt
Tel: +20 3 5921675
E-mail: [email protected]
Received date: August 20, 2016; Accepted date: September 13, 2016; Published date: September 15, 2016
Citation: Tohamy HG, Shourbela RM (2016) Pathological Investigations on Galilee Tilapia (Sarotherodon galilaeus) Following Chronic Exposure to Cadmium Chloride. J Aquac Res Development 7:446. doi:10.4172/2155-9546.1000446
Copyright: © 2016 Tohamy HG, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The morphopathological alterations of chronic cadmium (Cd) toxicity in Sarotherodon galilaeus were studied. 126 fish were used to determine 96 hrs LC50 of cadmium chloride, the obtained result was 28.3 mg/L. Forty-eight fish were used to induce chronic toxicity, twenty-four fish were exposed to 2.83 mg/L cadmium chloride for 8 weeks and other fish as control. Gills, hepatopancreas, posterior kidney and spleen were the most affected organs during chronic exposure. Eosinophilic granular cells (EGCs) infiltration and goblet cells hyperplasia in tips of primary lamellae, lamellar lifting, lamellar necrosis and Proliferative interlamellar hyperplasia with fusion in gills, hydropic degeneration and necrosis of the hepatic cells, hemorrhage and necrotic renal tubules and splenic necrosis and depletion of lymphocytes were recorded as histopathological changes.