alexa Patient’s Preferences for Management Options in Relation to Preterm Birth | OMICS International | Abstract
ISSN: 2157-7420

Journal of Health & Medical Informatics
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Research Article

Patient’s Preferences for Management Options in Relation to Preterm Birth

van der Ven AJ1, van Os M2, van den Wijngaard L3, Mochtar MH3, de Bekker-Grob EW4, Kazemier BM1, de Groot CJM2, Pajkrt E1, Mol BWJ5 and van Wely M3*

1Department of Obstetrics and Gynaecology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

2Department of Obstetrics and Gynaecology, VU University Medical Center, Amsterdam, The Netherlands

3Center for Reproductive Medicine, Dept. Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands

4Department of Public Health, Erasmus University MC, Rotterdam, The Netherlands

5The Robinson Institute, School of Paediatrics and Reproductive Health, University of Adelaide, 5000 SA , Australia

*Corresponding Author:
M van Wely
Center for Reproductive Medicine
Department of Obstetrics and Gynaecology
Academic Medical Center, University of Amsterdam
Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Tel: 31642238278
E-mail: [email protected]

Received date: May 27, 2015; Accepted date: June 05, 2015; Published date: June 11, 2015

Citation: van der Ven AJ, van Os M, van den Wijngaard L, Mochtar MH, de Bekker-Grob EW, et al. (2015) Patient’s Preferences for Management Options in Relation to Preterm Birth. J Health Med Informat 6:189. doi:10.4172/2157-7420.1000189

Copyright: © 2015 van der Ven AJ. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


To explore pregnant women’s preferences regarding cervical length measurement by ultrasound and treatment with progesterone in relation to preterm birth prevention we performed a discrete choice experiment. Four hospitals, four ultrasound centers and ten midwifery practices spread over the country participated in this study and distributed questionnaires among pregnant women between 15-36 weeks of gestation. Each questionnaire contained 16 choice sets with two screening or treatment options and one opt-out ‘no screening or treatment’ option. Women were asked to consider the following screening/treatment options 1) transvaginal or abdominal cervical length measurement, 2) vaginal or oral administration of progesterone, 3) short-term health risk and 4) long-term health risk for the child. The relative importance of the choices and trade-offs patients were willing to make were analyzed with panel-based mixed logit regression in STATA. Of the 156 questionnaires that were actually handed out, 138 were returned. Overall most respondents made trade-offs between attributes and all screening/treatment characteristics proved important in their decision making. Transvaginal cervical length measurements were not preferred (p=0.01) and was traded only in exchange for an absolute decrease of 6.5% (95% CI 2.6 – 10.4) in long-term neonatal complication rate. Previous experience with adverse neonatal outcome affected the preferences of the women.


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