alexa Pattern of Resistant Candida Infection: Case Series | OMICS International | Abstract
ISSN: 2161-0665

Pediatrics & Therapeutics
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Research Article

Pattern of Resistant Candida Infection: Case Series

Mazen Alessa* and Aditya Raina

Department of Pediatrics, Kuwait University, Kuwait

*Corresponding Author:
Mazen Alessa
Associate Professor, Department of Pediatrics
Faculty of Medicine, Kuwait University
P. O. Box 24923, Safat 13110, Kuwait
Tel: 965-25319486
Fax: 965-25338940
E-mail: [email protected]

Received date May 27, 2016; Accepted date June 14, 2016; Published date June 16, 2016

Citation: Alessa M, Raina A (2016) Pattern of Resistant Candida Infection: Case Series. Pediatr Ther 6:294. doi:10.4172/2161-0665.1000294

Copyright: © 2016 Alessa M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.


Background: Neonatal candidiasis is one of the common nosocomial infections in the neonatal units especially in the extremely low birth weight (ELBW) infants due to many factors mainly the intensive interventional care. Some of the cases can become resistant to the common antifungal treatment and therefore you have to change the treatment and minimize interventions.

Objectives: To study the pattern of resistant invasive Candida infections in a neonatal unit and to assess whether minimal intervention in very low birth weight (VLBW) and extremely low birth weight babies contributes to clearance of infection.

Methods: Cases of very low birth weight and extremely low birth weight, who had persistent invasive Candida infection and were extensively treated and fully investigated in a neonatal unit at Maternity Hospital in Kuwait, were prospectively followed-up for over two years. Risk factors leading to Candida infection and its persistence were assessed.

Results: All of the six cases with persistent Candida infection cleared their infection only after they were transferred from intensive care unit to the special care baby unit with minimal invasive intervention. Conclusion: This study showed that minimal interventions in very low birth weight and extremely low birth weight neonates can lead to improved outcome by reducing number of risk factors that are associated with invasive Candida infection or with its persistence.


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