alexa Pauci Antibody Anti-GBM Nephritis: A Case Report
ISSN: 2161-0959

Journal of Nephrology & Therapeutics
Open Access

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Case Report

Pauci Antibody Anti-GBM Nephritis: A Case Report

Upma Narain1* and Arvind Gupta2

1Microbiologist and Immunologist, Tejas Microdiagnostic, Uttar Pradesh, India

2Professor, Department of Nephrology, Moti Lal Nehru Medical College, Uttar Pradesh, India

*Corresponding Author:
Upma Narain
Microbiologist and Immunologist
Tejas Microdiagnostic
Jawahar Lal Nehru Road
Allahabad, Uttar Pradesh-211002, India
Tel: +91-9415253337
E-mail: [email protected]

Received Date: December 09, 2015; Accepted Date: December 16, 2015; Published Date: December 23, 2015

Citation: Narain U, Gupta A (2015) Pauci Antibody Anti-GBM Nephritis: A Case Report. J Nephrol Ther 6:230. doi:10.4172/2161-0959.1000230

Copyright: © 2015 Narain U, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Anti-glomerular basement membrane (GBM) disease is characterized by autoantibodies directed against the anti-GBM antigen, which is part of the non-collagenous domain of the alpha 3(IV) collagen chain. These antibodies bind to the GBM and most patients show rapid progressive form of glomerulonephritis. The alveolar basement membrane also contain the anti-GBM antigen, and some patients pulmonary haemorrhage

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