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Journal of Nephrology & Therapeutics

ISSN: 2161-0959

Open Access

Pauci Antibody Anti-GBM Nephritis: A Case Report

Abstract

Upma Narain *,Arvind Gupta

Anti-glomerular basement membrane (GBM) disease is characterized by autoantibodies directed against the anti-GBM antigen, which is part of the non-collagenous domain of the alpha 3(IV) collagen chain. These antibodies bind to the GBM and most patients show rapid progressive form of glomerulonephritis. The alveolar basement membrane also contain the anti-GBM antigen, and some patients pulmonary haemorrhage

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