Journal of Clinical & Medical Genomics

Cardiac Resynchronization Therapy and Left Ventricular Diastolic Function

Abstract

Kammoun I, Marrakchi S and Kachboura S

Cardiac resynchronization therapy (CRT) improves systolic performance in heart failure (HF). However, the effects of CRT on left ventricular diastolic function were variable and not fully understood.

The available studies used different diastolic parameters derived from pulse and tissue Doppler techniques and more recently from deformation data.

The most studies showed that CRT improves diastolic function (data are more controversial regarding relaxation) but this seems to be dependent on improvement in systolic function.