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Comparative Action of Sedative Hypnotics on Neurophysiology of Sleep | OMICS International | Abstract
ISSN: 2167-0277

Journal of Sleep Disorders & Therapy
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Review Article

Comparative Action of Sedative Hypnotics on Neurophysiology of Sleep

Ashish Kumar U1 and Princy Louis Palatty2*
13rd Year MBBS Student, Father Muller Medical College, Kankanady, Mangalore, Karnataka, India
2Department of Pharmacology, Father Muller Medical College, Kankanady, Mangalore, Karnataka, India
Corresponding Author : Princy Louis Palatty
Professor, Department of Pharmacology
Father Muller Medical College, Kankanady
Mangalore, Karnataka, India
Tel: +91 98451 04505, 0824-22380000
Fax: 0824-2436661
E-mail: [email protected]
Received June 20, 2013; Accepted October 22, 2013; Published October 26, 2013
Citation: Ashish Kumar U, Palatty PL (2013) Comparative Action of Sedative Hypnotics on Neurophysiology of Sleep. J Sleep Disord Ther 2:150. doi:10.4172/2167-0277.1000150
Copyright: © 2013 Ashish Kumar U, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


In spite of tremendous advances in medical science, sleep has not been understood completely. The causes for many of parasomnias are still not evident. Even then these parasomnias are treated with different drugs, one of the major groups among them being sedative hypnotics. The use of sedative hypnotics are always associated with adverse effect, and there is many a times loss of the normal sleep architecture. This causes problems both during drug intake and with the withdrawal of drugs. Hence the need for today is the use of sedative hypnotics with minimum alteration in sleep architecture. The changes in the sleep architecture with the administration of sedative hypnotics can be recorded with the changes in the normal sleep EEG pattern. In this review effort has been made in elaborating the various sleep EEG pattern changes, resulting with the use of different groups of sedative hypnotic drugs with a brief note on their respective mechanism of action and pharmacological properties.


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