Pediatrics & Therapeutics
Open Access

Abstract

Pediatric Oncology Drug Development: A Case Report and Pathways Forward

John M. Goldberg and Joseph Panoff

In this case report, we briefly review the treatment of a patient with metastatic, refractory Ewing's sarcoma who was treated on a Phase I clinical trial before she died from progressive disease. The case illustrates the need for early phase clinical trials programs in pediatric oncology, and the way in which investigators approach such programs.