alexa Effect of Hydroxyapatite on Reaction of Dicalcium Phosphate Dihydrate DCPD) and Fluoride Ion | OMICS International | Abstract

Bioceramics Development and Applications
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Research Article

Effect of Hydroxyapatite on Reaction of Dicalcium Phosphate Dihydrate DCPD) and Fluoride Ion

Masamoto Tafu*, Takaaki Masutani, Yuka Takemura, Takeshi Toshima and Tetsuji Chohji

Toyama National College of Technology, Institute of National Colleges of Technology, 13 Hongo-machi, Toyama 939-8630, 305-8566, Japan

Corresponding Author:
Masamoto Tafu
Toyama National College of Technology
Institute of National Colleges of Technology
Japan, 13 Hongomachi, Toyama 939-8630, 305-8566, Japan
E-mail: [email protected]

Received date: June 21, 2013; Accepted date: July 29, 2013; Published date: October 24, 2013

Citation: Tafu M, Masutani T, Takemura Y, Toshima T, Chohji T (2013) Effect of Hydroxyapatite on Reaction of Dicalcium Phosphate Dihydrate (DCPD) and Fluoride Ion. Bioceram Dev Appl S1:015. doi:10.4172/2090-5025.S1-015

Copyright: © 2013 Tafu M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


DCPD, dicalcium phosphate dihydrate (CaHPO4•2H2O) reacts with fluoride ion in an aqueous solution, and forms fluorapatite (FAp, Ca10(PO4)6F2). In previous study, we have found that DCPD does not react with fluoride ion directly, but show few hours of induction period by reaction with fluoride. In this study, effect of hydroxyapatite (HA, Ca10(PO4)6(OH)2) on the reactivity of DCPD with fluoride ion was investigated. By mixing HA with DCPD, it was appeared that the induction period of the reaction was shortened. Morphology of the obtained FAp was similar to HA paricles. We carried on coating of HA on the DCPD particle by soaking DCPD in simulated body fluid (SBF, Kokubo Solution). By coating HA on DCPD particles, particle morphology of the obtained FAp was consistency to the DCPD particles. These results suggest that the shape and particle size of FAp after reaction of DCPD is controllable by DCPD particle as template, and coating with HA.


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