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Perianal Extramammary Paget's Disease: Diagnosis, Treatment and Prognosis | OMICS International | Abstract
ISSN: 2157-7099

Journal of Cytology & Histology
Open Access

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Case Report

Perianal Extramammary Paget's Disease: Diagnosis, Treatment and Prognosis

Francesca De Felice1*, Daniela Musio1, Rossella Caiazzo1, Alessandra Pieroni1, Michele Carnevale1, Francesca Salerno1 and Vincenzo Tombolini1,2

 

1Department of Oncological and Radiological Sciences Anatomy and Pathological , Catterdra of Radiotherapy, University of Rome " Sapienza" Viale Regina Elena 155, 00161 Rome, Italy

2Spencer-Lorillard Foundation, Viale Regina Elena 262,00161 Rome, Italy

*Corresponding Author:
Francesca De Felice
Department of Oncological and Radiological Sciences Anatomy and Pathological
Catterdra of Radiotherapy
University of Rome " Sapienza" Viale Regina Elena 155, 00161 Roma, Italy
Tel: 06-49973404
Fax: 0649973411
E-mail: [email protected]

Received Date: July 23, 2014; Accepted Date: September 09, 2014; Published Date: September 11, 2014

Citation: De Felice F, Musio D, Caiazzo R, Pieroni A, Carnevale M, et al. (2014) Perianal Extramammary Paget’s Disease: Diagnosis, Treatment and Prognosis. J Cytol Histol 5:277. doi:10.4172/2157-7099.1000277

Copyright: © 2014 Felice FD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: To make an update on the state of knowledge on perianal extramammary Paget’s disease.
Case presentation:
We report one case as an illustration of this rare, slow-growing and occasionally metastasizing entity. The standard treatment is a local surgical excision. Radiation therapy is recommended as primary treatment in inoperable patients, and as alternative to surgery for recurrence disease previously excised or in case of mutilating surgery.
Conclusions: Definitive conclusion cannot be drawn. Clinical trials are required to test whether radiation therapy is advantageous as primary treatment approach, compared to surgery.

Keywords

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