Perianal Extramammary Paget's Disease: Diagnosis, Treatment and Prognosis
- *Corresponding Author:
- Francesca De Felice
Department of Oncological and Radiological Sciences Anatomy and Pathological
Catterdra of Radiotherapy
University of Rome " Sapienza" Viale Regina Elena 155, 00161 Roma, Italy
E-mail: [email protected]
Received Date: July 23, 2014; Accepted Date: September 09, 2014; Published Date: September 11, 2014
Citation: De Felice F, Musio D, Caiazzo R, Pieroni A, Carnevale M, et al. (2014) Perianal Extramammary Paget’s Disease: Diagnosis, Treatment and Prognosis. J Cytol Histol 5:277. doi:10.4172/2157-7099.1000277
Copyright: © 2014 Felice FD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: To make an update on the state of knowledge on perianal extramammary Paget’s disease.
Case presentation: We report one case as an illustration of this rare, slow-growing and occasionally metastasizing entity. The standard treatment is a local surgical excision. Radiation therapy is recommended as primary treatment in inoperable patients, and as alternative to surgery for recurrence disease previously excised or in case of mutilating surgery.
Conclusions: Definitive conclusion cannot be drawn. Clinical trials are required to test whether radiation therapy is advantageous as primary treatment approach, compared to surgery.