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Journal of Anesthesia & Clinical Research
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  • Review   
  • J Anesth Clin Res 2019, Vol 10(5): 893

Perioperative Management of Diabetes Mellitus: A Review

Mariana Raquel Moreira Azevedo1 and Humberto S Machado2,3*
1Department of Anesthesiology, Abel Salazar Institute of Biomedical Sciences, University of Porto, Portugal
2Department of Anesthesiology, University Hospital Center of Porto, Porto, Portugal
3Center for Clinical Research in Anesthesiology, University Hospital Center of Porto, Porto, Portugal
*Corresponding Author : Dr. Humberto S Machado, Department of Anesthesiology, University Hospital Center of Porto, Portugal Largo Professor Abel Salazar, 4099-001 Porto, Portugal, Tel: +351.935848475, Email: [email protected]

Received Date: Apr 19, 2019 / Accepted Date: May 24, 2019 / Published Date: May 31, 2019


Introduction: Diabetes Mellitus (DM) is frequently observed in surgical patients and relates to an increase in perioperative morbidity and mortality. Disease, anesthesia and surgery result in dysglycemia (hypo and/or hyperglycemia), which is one of the worse prognostic factors. The objective of this study is to review the specific needs of the diabetic surgical patient in the perioperative period, regarding its optimization.

Methods: Scientific studies (n=89) were obtained through PubMed, Google Scholar and Google, between 2008 and 2018.

Results: Actions proposed in order to reduce perioperative complications in the diabetic patient. Preoperative period: an anesthetic evaluation, discontinuation of OADs and fast-acting insulin, prioritization of diabetics in the surgery list, cancellation of non-urgent procedures when there are metabolic abnormalities and poor glycemic control and promotion of gastric emptying due to gastrointestinal autonomic dysfunction. Intraoperative period: the use of IV perfusion of insulin for glycemic control in major surgeries, the use of glycoside sera in cases of prolonged fasting and/or IV insulin perfusion, hourly glycemic monitoring, a glycemic goal between 80-180 mg/dl with correction of hyperglycemias with insulin, and the use of a rapid-sequence intubation when there is risk of aspiration. Postoperative period: the early return to oral nutrition and the restitution of OADs and insulin with the onset of food intake, multimodal analgesia and antiemetic prophylaxis, the correct transition from IV perfusion to subcutaneous insulin and pre-discharge therapeutic optimization.

Discussion: Several studies have shown a correlation between dysglycemia and postoperative morbidity and mortality. Nevertheless, the ideal glycemic range and the best glycemic management strategy remain indeterminate.

Conclusion: Studies that establish specific measures and universal cut-offs are scarce. There is a need for clearer and guidelines to minimize perioperative complications. It is also important that diabetic patients have the capacity to manage their own disease, to facilitate their optimization in the surgical context.

Keywords: Diabetes mellitus; Perioperative management; Anesthesia; Preoperative; Postoperative; Surgery

Citation: Azevedo MRM, Machado HS (2019) Perioperative Management of Diabetes Mellitus: A Review. J Anesth Clin Res 10: 893.

Copyright: © 2019 Azevedo MRM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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