alexa Perioperative Management of Patient with Factor XI Defi
ISSN: 2155-6148

Journal of Anesthesia & Clinical Research
Open Access

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Case Report

Perioperative Management of Patient with Factor XI Deficiency Undergoing Total Knee Arthroplasty

Eric Kamenetsky1* and Sherif Afifi2

1Department of Anesthesiology, McGaw Medical Center of Northwestern University, Chicago, USA

2Department of Anesthesiology, Northwestern Memorial Hospital, Chicago, USA

*Corresponding Author:
Eric Kamenetsky
Department of Anesthesiology,Northwestern Memorial Hospital
251 E. Huron, F5-704, Chicago, IL 60611, USA
Tel: 312-695-0061
Fax: 312-695-9013
E-mail: [email protected]

Received date: September 18, 2014; Accepted date: November 15, 2014; Published date: November 27, 2014

Citation: Kamenetsky E, Afifi S (2014) Perioperative Management of Patient with Factor XI Deficiency Undergoing Total Knee Arthroplasty. J Anesth Clin Res 5:471. doi: 10.4172/2155-6148.1000471

Copyright: © 2014 Kamenetsky E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Factor XI (FXI) deficiency is a rare, inherited bleeding disorder that is typically asymptomatic and presents with unexpected bleeding after surgery or trauma. We present a patient with FXI deficiency that underwent total knee arthroplasty (TKA) under general anesthesia and received peripheral nerve blocks for postoperative analgesia. We also present a review of literature focused on presentation of FXI deficiency in various surgical settings and choices of perioperative anesthetic management.


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