Perspectives on Carbon Nanotube-Based Scaffolds in Nerve Tissue Engineering
Shang-Tian Yang* and Ru Zang
Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, USA
- Corresponding Author:
- Dr. Shang-Tian Yang
Professor, Department of Chemical and Biomolecular Engineering
The Ohio State University, 140 West 19th Avenue
Columbus, Ohio 43210, USA
Tel: (614) 292-6611
Fax: (614) 292-3769
E-mail: [email protected]
Received date: December 14, 2011; Accepted date: December 20, 2011; Published date: December 22, 2011
Citation: Yang S, Zang R (2012) Perspectives on Carbon Nanotube-Based Scaffolds in Nerve Tissue Engineering. J Tissue Sci Eng 3:e108. doi:10.4172/2157-7552.1000e108
Copyright: © 2012 Yang S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
To improve the health and quality of life of patients suffering from neural degeneration diseases or brain and spinal cord injuries, much research has been dedicated to the repairing and regeneration of neural tissues. Although allogenic grafts have no supply limitation, they often cause undesirable immune responses. Thus, autologous grafts are usually used to treat neural defects. However, the short life of nerves and a mismatch of nerve cable dimension between the donor graft and the receptor nerve limit its clinical applications. Nerve tissue engineering has emerged as a highly promising alternative strategy to neural therapy, aimed at rebuilding the lesioned circuits of the central and peripheral nervous systems, while minimizing body’s immune responses with engineered nerves.