alexa PET/CT and MRI in Bladder Cancer | OMICS International | Abstract
ISSN: 1948-5956

Journal of Cancer Science & Therapy
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Research Article

PET/CT and MRI in Bladder Cancer

Kirsten Bouchelouche1*, Baris Turkbey2and Peter L Choyke2
1Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Skejby, Denmark
2Molecular Imaging Program, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA
Corresponding Author : Kirsten Bouchelouche, MD, DMSc
Chief Physician
Department of Nuclear Medicine & PET Centre
Aarhus University Hospital, Skejby
Brendstrupgaardsvej 100, DK-8200 Aarhus, Denmark
Tel: +45 20 29 19 03
E-mail: [email protected]
Received June 07, 2012; Accepted July 28 2012; Published July 30, 2012
Citation: Bouchelouche K, Turkbey B, Choyke PL (2012) PET/CT and MRI in Bladder Cancer. J Cancer Sci Ther S14:001. doi:10.4172/1948-5956.S14-001
Copyright: © 2012 Bouchelouche K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Bladder Cancer (BCa) is the most common malignancy arising from the urinary tract. One of the mainstays of diagnosis, staging, and therapeutic decision-making for BCa is accurate and appropriate imaging. The ability to identify metastatic disease preoperatively is of utmost importance in determining treatment. Advances in standard cross sectional imaging techniques like Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) have improved imaging of bladder cancer. Over the last decade, 18F-fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) in combination with CT (18F-FDG PET/CT) has become an important non-invasive imaging modality for the preoperative staging of various malignancies. 18F-FDG PET/CT is useful for detection of metastatic disease in BCa, but the ability to detect primary bladder wall lesions remains to be elucidated. To overcome the problem with urinary excretion of 18F-FDG, new PET tracers are being tested. MRI is an accurate technique for the local staging of BCa due to its superior spatial and contrast resolution. Anatomical MRI has a modest utility in NMstaging of BCa. However, incorporation of functional MR techniques, such as diffusion weighted MRI can improve the results for lesion detection and staging and multi-parametric MRI`s role is yet to be explored widely. The aim of this review is to present the recent advances in PET/CT and MRI in BCa, with particular focus on improvements in staging.

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