Pharmacogenetics Variations in AnesthesiaAvinash Puri*
Department of Anesthesia and Intensive Care, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India
- *Corresponding Author:
- Avinash Puri
Department of Anesthesia and Intensive Care
Post Graduate Institute of Medical Education and Research
Chandigarh, 160012, India
E-mail: [email protected]
Received date: June 22, 2012; Accepted date: August 09, 2012; Published date: August 29, 2012
Citation: Puri A (2012) Pharmacogenetics Variations in Anesthesia. J Anesth Clin Res 3:233. doi: 10.4172/2155-6148.1000233
Copyright: © 2012 Puri A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Pharmacogenetics is an emerging discipline that attempted to understand the hereditary basis for differences in responsiveness or inter-individual variation to therapeutic agents. It is the study of variability in drug response as a result of heredity factors. The importance for pharmacogenetics for the clinician is to enable optimum therapeutic efficacy, to avoid toxicity of those drugs whose metabolism is catalyzed by polymorphic isoenzymes, and to contribute to the rational design of new drugs.