alexa Phenytoin in the Treatment of Osmophobia in Migraine Patient: A Case Report | OMICS International
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Phenytoin in the Treatment of Osmophobia in Migraine Patient: A Case Report

Raimundo Pereira Silva-Néto*
Department of Neuropsychiatry, Federal University of Pernambuco, Brazil
*Corresponding Author : Raimundo Pereira Silva-Néto
Department of Neuropsychiatry
Federal University of Pernambuco, Brazil
Tel: (81) 2126.8000
E-mail: [email protected]
Received: January 25, 2016 Accepted: March 22, 2016 Published: March 26, 2016
Citation: Silva-Néto RP (2016) Phenytoin in the Treatment of Osmophobia in Migraine Patient: A Case Report. J Clin Case Rep 6:749. doi:10.4172/2165-7920.1000749
Copyright: © 2016 Silva-Néto RP. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Osmophobia is defined as intolerance to odors and it is associated to primary headaches, particularly to migraine with or without aura. It occurs during headache attacks and/or in the period between headache attacks. It is not yet known specific treatment for osmophobia. Case: We describe a case of a 38-year-old woman diagnosed with migraine without aura according to ICHD- 3 criteria. She complained of severe osmophobia both during and between headache attacks. In the pain-free period, she had extreme intolerance to any odors. Physical examination and imaging were unremarkable. Several prophylactic treatments of migraine were administered the past two years. There was a marked improvement in the frequency and intensity of headache attacks, but osmophobia remained unchanged. She would like to treat only her osmophobia. A prophylactic treatment with phenytoin was started to osmophobia, with disappearance of this symptom within 90 days. Conclusion: From our experience in this case, phenytoin should be considered as possible prophylactic treatment for osmophobia between headache attacks in migraine patients.

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