alexa Phylogenetic Analysis of Genetic Diversity of Hemolysins in Leptospira
ISSN: 0974-276X

Journal of Proteomics & Bioinformatics
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Phylogenetic Analysis of Genetic Diversity of Hemolysins in Leptospira

Tejpreet Chadha1* and Alexandre Trindade A2

1Department of Biological Sciences, Texas Tech University, BOX 43131, Lubbock, TX 79409, USA

2Department of Mathematics and Statistics, Texas Tech University, Broadway and Boston, Lubbock, TX 79409, USA

*Corresponding Author:
Tejpreet Chadha
Department of Biological Sciences
Texas Tech University
BOX 43131, Lubbock, TX 79409, USA
E-mail: [email protected]

Received Date: May 16, 2012; Accepted Date: June 28, 2012; Published Date: July 05, 2012

Citation: Chadha T, Alexandre Trindade A (2012) Phylogenetic Analysis of Genetic Diversity of Hemolysins in Leptospira. J Proteomics Bioinform 5: 152-154. doi: 10.4172/jpb.1000228

Copyright: © 2012 Chadha T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Leptospirosis is a zoonotic disease distributed worldwide. It has now been identified as one of the emerging infectious diseases. The genomic sequences of Leptospira species have helped to identify the genetic diversity of hemolysins among different pathogenic and saprophytic Leptospira species. The phylogenetic analysis reveals that hemolysin SphH, a pore-forming protein on various mammalian cells in pathogenic Leptospira, does not show significant similarity to hemolysins in saprophytic Leptospira biflexa. The Leptospira interrogans hemolysin gene also does not show significant similarity to L. biflexa and Leptospira borgpetersenii. The genetic diversity among hemolysin genes in Leptospira suggests that the gain of more hemolysin genes during the course of their evolution may have contributed to their virulence.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

phar[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords