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ISSN: 2329-6836

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Research Article

Phytochemical Evaluation and Analgesic Activity of Pentas lanceolata Leaves

Suman D1, Vishwanadham Y1*, Kumaraswamy T1, Shirisha P2 and Hemalatha K1
1 Department of Pharmaceutical Chemistry, Malla Reddy College of Pharmacy, Secunderabad-14, Telangana, India
2 Department of Pharmaceutical Chemistry, Anurag College of Pharmacy, Kodad, Nalgonda, Telangana, India
Corresponding Author : Vishwanadham Y
Department of Pharmaceutical Chemistry
Malla Reddy College of Pharmacy
Secunderabad-14, Telangana, India
Tel: 040-64634235
E-mail: [email protected]
Received April 28, 2014; Accepted May 19, 2014; Published May 22, 2014
Citation: Suman D, Vishwanadham Y, Kumaraswamy T, Shirisha P, Hemalatha K (2014) Phytochemical Evaluation and Analgesic Activity of Pentas lanceolata Leaves. Nat Prod Chem Res 2:135. doi: 10.4172/2329-6836.1000135
Copyright: © 2014 Vishwanadham Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

In the present study, different solvent extracts of “Pentas lanceolata” leaves (family Rubiaceae) were under taken for phytochemical investigation and subjected to analgesic activity. The preliminary and phytochemical investigation showed presence of sterols, triterpinoids, glycosides, flavonoids, alkaloids, carbohydrates, resins. The different solvent like n-Hexane, ethyl acetate, ethanolic extracts of compounds from “Pentas lanceolata” leaves. Analgesic activity was performed by the acetic acid induced writhing method. Due to the presence of the above compounds in n-hexane and ethanol extracts showed significant activity (P<0.01) when compared with the standard (aspirin) whereas ethyl acetate extract showed moderate to weak (P<0.05) activity.

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