alexa PHYTOCHEMICAL SCREENING AND TOXICITY STUDIES ON THE LEA


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Research Article

PHYTOCHEMICAL SCREENING AND TOXICITY STUDIES ON THE LEAVES OF MANNIOPHYTON FULVUM

1*Agbaire P.O., 2Emudainohwo J.O.T and 3Peretiemo-Clarke, B. O
  1. Department of Chemistry, Faculty of Sciences, Delta State University, Abraka, Nigeria.
  2. Department of Pharmacology and Therapeutics Delta State University, Abraka, Nigeria.
  3. Department of Chemistry, Faculty of Sciences, Delta State University, Abraka, Nigeria.
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Abstract

With regards to current drug development strategies, natural products have continually provided an essential source for new drugs. In this study, the phytochemical constituents present in the leaf extract of Manniophyton fulvum were screened and its toxicological properties in vitro were also established. The phytochemical screening of the ethanolic leaf extract of Manniophyton fulvum revealed the presence of alkaloids, saponins, sterols/terpenes, reducing sugars, anthraquinones, and cardiac glycosides. The leaf extract produced toxicity at a dose of 1050 mg/kg. The observed effects could not be unconnected to the presence of the phytochemical constituents in the extract. The outcome of this study lends support to the trado-medicinal uses of Manniophyton fulvum in the treatment of various medical conditions.

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