alexa Phytochemical Screening of Medicinal Plants of the Kaka
ISSN: 2167-0412

Medicinal & Aromatic Plants
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Research Article

Phytochemical Screening of Medicinal Plants of the Kakamega Country, Kenya Commonly Used against Cancer

Dominic O Ochwang’I1*, Charles N Kimwele1, Jemimah A Oduma1, Peter K Gathumbi2, Stephen G Kiama1 and Thomas Efferth3*

1Department of Veterinary Anatomy and Physiology, University of Nairobi, Nairobi, Kenya

2Department of Veterinary Pathology, Parasitology and Microbiology, University of Nairobi, Nairobi, Kenya

3Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany

Corresponding Author:
Thomas Efferth
Department of Pharmaceutical Biology
Institute of Pharmacy and Biochemistry
Johannes Gutenberg University, Staudinger
Weg 5, 55128 Mainz, Germany
Tel: +493925751
E-mail: [email protected]
Dominic O Ochwang’I
Department of Veterinary Anatomy and
Physiology, University of Nairobi, Nairobi, Kenya
Tel: +254723759997
E-mail: [email protected]

Received date: November 22, 2016; Accepted date: December 02, 2016; Published date: December 08, 2016

Citation: Ochwang’I DO, Kimwele CN, Oduma JA, Gathumbi PK, Kiama SG, et al. (2016) Phytochemical Screening of Medicinal Plants of the Kakamega Country, Kenya Commonly Used against Cancer. Med Aromat Plants (Los Angel) 5:277. doi: 10.4172/2167-0412.1000277

Copyright: © 2016 Ochwang’I DO, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Phytochemical constituents of 35 selected anticancer medicinal plant extracts were analyzed by thin layer chromatography (TLC) for alkaloids, anthraquinones, xanthines, valepotriates, cardiac glycosides, flavonoids, essential oils, coumarins, lignans, saponins and arbutin compounds. These plants sourced from Kakamega tropical rain forest have been previously reported to be used for cancer treatment in the Kakamega County, Kenya. The medicinal plants investigated were Harungana madagascariensis Lam. ex poir, Fuerstia africana T.C.E. Fr., Sida rhombifolia L., Zanthoxylum rubescens Hook. f, Bridelia micrantha (Hochst.) Baill, Juniperus procera Endl., Tragia brevipes Pax, Phyllanthus sapialis, Conyza sumatrensis, Momordica foetida Schumach., Synsepalum cerasiferum Synonym: Afrosersalisia cerasifera (Welw.) Aubrev, Aloe volkensii Engl, Aeschynomene abyssinica (A. Rich.) Vatke, Futumia africana Benth. Cyphostemma serpens (A. Rich), Ipomoea cairica (L.), Spathodea campanulata P. Beauv. ssp. nilotica (Seem), Abrus precatorius L. ssp africanus Verdc., Triumfetta rhomboidea Jacq., Psydrax schimperiana (A.Rich), Ficus thonningii, Rotheca myricoides (Hochst. Steane and Mabb), Croton macrostachyus Delile, Vernonia lasiopus O Hoffin, Albizia gummifera (J.F. Gmel.), Zanthoxylum gilletii (De Wild.) P.G. Waterman, Microglossa pyrifolia (Lam.)Kuntze, Senna didymobotyra (Fresen.) Irwinand Barneby, Trichilia emetica Vahl, Entada abyssinica Steud.ex A.Rich., Shirakiopsis elliptica (Hochst.)Esser Synonym: Sapium ellipticum (Hochst.kraus) Pax, Ocimum gratissimum L.Suave wiild O.tomentosum oliv., Prunus africana (Hook.f.) Kalkman, Phyllanthus fischeri Pax and Olea hotch spp. Hochstetteri. The phytochemical distribution in the 35 plants included:71.4% alkaloids, 57.1% anthraquinones, 94.2% xanthines, 82.8% valepotriates, 94.2% cardioactive glycosides, 82.8% flavonoids, 77.1% essential oils, 85.7% coumarin drugs, 68.5% lignans, 80% saponins and 62.85% arbutin drugs. Our findings provided evidence that crude organic and inorganic solvent extracts of these tested plants contain medicinally important bioactive compounds and provide a rational basis for their use in traditional medicine.


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