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ISSN: 2161-0444

Medicinal Chemistry
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Review Article

Phytochemistry and Therapeutic Potential of Medicinal Plant: Dioscorea bulbifera

Sougata Ghosh1, Vijay Singh Parihar2, Piyush More1, Dilip D Dhavale2 and Balu A Chopade3*

1Institute of Bioinformatics and Biotechnology, University of Pune, Pune-411007, India

2Department of Chemistry, University of Pune, Pune-411044, India

3Department of Microbiology, University of Pune, Pune-411007, India

*Corresponding Author:
Balu A Chopade
Professor, Department of Microbiology
University of Pune, Pune 411007, India
Tel: +91 020 25690643
Fax: +91 020 25690087
E-mail: [email protected]; [email protected]

Received date: March 05, 2015; Accepted date: April 09, 2015; Published date: April 11, 2015

Citation: Ghosh S, Parihar VS, More P, Dhavale DD, Chopade BA (2015) Phytochemistry and Therapeutic Potential of Medicinal Plant: Dioscorea bulbifera. Med chem 5:154-159. doi:10.4172/2161-0444.1000259

Copyright: © 2015 Ghosh S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Dioscorea bulbifera is an immensely important medicinal plant which is extensively used in both Indian and Chinese system of traditional medicine. It is found in many parts of the world and has gained wide attention not only for health care but also as a food crop. It has attracted scientific interest owing to its numerous therapeutic applications in various pathophysiological conditions like ulcers, sores, wound, spasms, dysentery, diabetes and cancer. Spectacular success in extensive research particularly within last two decades has proven that these activities are attributed to its unique phytochemistry. Bioactive components from D. bulbifera have exhibited anti-oxidant, antiinflammatory, antibacterial, plasmid curing, antidiabetic and anticancer activities. It has become a model system in nanobiotechnology as it harbours phytochemicals with reducing, capping and shape modulating efficiencies. Numerous studies, either separately or in association, have aimed to explain the chemical composition and mechanisms behind its pharmacognostic significance. Similarly, many reports have documented and validated the claimed traditional usage by providing a strong scientific rationale. However, there is no review published on its in vitro, in vivo and in silico applications along with detailed phytochemistry. In view of the background, this review elaborates the complete phytochemistry of D. bulbifera with therapeutic importance.

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