alexa Inactivation of Human Rhinovirus due to Heat, UV Irradiation and Chemical Disinfectants | OMICS International| Abstract

ISSN: 1948-5964

Journal of Antivirals & Antiretrovirals

  • Research Article   
  • J Antivir Antiretrovir 2017, Vol 9(4): 170
  • DOI: 10.4172/1948-5964.1000170

Inactivation of Human Rhinovirus due to Heat, UV Irradiation and Chemical Disinfectants

Yan-Hai Wang#, Xin-Ling Wang#, Juan Song, Qin-Qin Song, Xiao-Nuan Luo, Dong Xia and Jun Han*
State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Pre, 155 Changbai Road, 102206 Beijing, China
#Contributed equally to this work
*Corresponding Author : Jun Han, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, 102206 Beijing, China, Tel: 86-010-58900680, Fax: 86-010-58900680, Email: [email protected]

Received Date: Nov 25, 2017 / Accepted Date: Dec 19, 2017 / Published Date: Dec 28, 2017

Abstract

To evaluate and understand inactivation of HRV under many physical conditions and chemical agents, HRV86 were selected to expose with temperature, ultraviolet light (UV), Sodium hypochlorite, Virkon S, Peracetic acid (PAA), Glutaraldehyde and Ethanolin, respectively. The inactivation of HRV was analyzed by infectivity of the viral strains on the HeLa cells. Our research found the rhinovirus was very sensitive to temperature changes. Viral infectivity thoroughly lost after HRV86 was treated at 60°C for 10 min or UV irradiation for 45 min or longer. Virus also was completely inactivated after exposure to sodium hypochlorite (0.1 g/L) beyond 10 min, glutaraldehyde (10 g/L) for 5 min, Virkon-S (5 g/L) for 10 min, PAA (3 g/L) for 2 min, or 75% alcohol for 5 min or longer. The results provided the essential information for prevention and intervention of common cold.

Keywords: Chemical disinfectants; Rhinovirus; Inactivation; Thermal; UV irradiation

Citation: Wang YH, Wang XL, Song J, Song QQ, Luo XN, et al. (2017) Inactivation of Human Rhinovirus due to Heat, UV Irradiation and Chemical Disinfectants. J Antivir Antiretrovir 9: 96-101. Doi: 10.4172/1948-5964.1000170

Copyright: ©2017 Wang YH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Select your language of interest to view the total content in your interested language

Post Your Comment
Share This Article
Recommended Conferences
Article Usage
  • Total views: 859
  • [From(publication date): 0-2017 - Jul 23, 2018]
  • Breakdown by view type
  • HTML page views: 821
  • PDF downloads: 38
Leave Your Message 24x7