Plasmocytoid Dendritic Cells Leukemia: A Rare Presentation
- *Corresponding Author:
- Imane Tlamçani
Laboratory of Hematology
CHU Hassan II Fez, Morocco
Tel : 00212661530505
E-mail : [email protected]
Received date: January 27, 2014; Accepted date: February 24, 2014; Published date: February 27, 2014
Citation: Imane T, Yahyaoui G, Hassani MA, Benjelloun S, Najoua B, et al. (2014) Plasmocytoid Dendritic Cells Leukemia: A Rare Presentation. J Leuk (Los Angel) 2:131. doi: 10.4172/2329-6917.1000131
Copyright: © 2014 Imane T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author and source are credited.
The plasmacytoid dendritic cells leukemia is a rare hematolymphoid neoplasm with a very poor prognosis, where skin involvement is common. It is a malignant proliferation developed at the expense of hematopoietic cells of the white blood cells, proximate to normal plasmacytoid dendritic cells. The phenotype of tumor cells initially described was CD4 + CD56 +, without T marker expression. CD56- forms have also been reported, even fewer without skin involvement. More specific markers are expressed by tumor cells: CD123, BDCA2, BDCA4. We report an unusual presentation of this entity, but without skin lesions. The diagnosis of plasmacytoid dendritic cells leukemia was made on the cytological and immunophenotypic data given.