Plasmocytoid Dendritic Cells Leukemia: A Rare Presentation
- *Corresponding Author:
- Imane Tlamçani
Laboratory of Hematology
CHU Hassan II Fez, Morocco
Tel : 00212661530505
E-mail : [email protected]
Received date: January 27, 2014; Accepted date: February 24, 2014; Published date: February 27, 2014
Citation: Imane T, Yahyaoui G, Hassani MA, Benjelloun S, Najoua B, et al. (2014) Plasmocytoid Dendritic Cells Leukemia: A Rare Presentation. J Leuk (Los Angel) 2:131. doi: 10.4172/2329-6917.1000131
Copyright: © 2014 Imane T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author and source are credited.
;The plasmacytoid dendritic cells leukemia is a rare hematolymphoid neoplasm with a very poor prognosis, where skin involvement is common. It is a malignant proliferation developed at the expense of hematopoietic cells of the white blood cells, proximate to normal plasmacytoid dendritic cells. The phenotype of tumor cells initially described was CD4 + CD56 +, without T marker expression. CD56- forms have also been reported, even fewer without skin involvement. More specific markers are expressed by tumor cells: CD123, BDCA2, BDCA4. We report an unusual presentation of this entity, but without skin lesions. The diagnosis of plasmacytoid dendritic cells leukemia was made on the cytological and immunophenotypic data given.