Pleurotus florida Aqueous Extracts and Powder Influence Lipid Profile and Suppress Weight Gain in Rats Fed High Cholesterol DietEdith NF*, Elias EL and Carl MFM
National School of Agro-Industrial Sciences (ENSAI), Department of Food Science and Nutrition, University of Ngaoundere, PO Box 455, Ngaoundere, Cameroon
- *Corresponding Author:
- Edith NF
National School of Agro-Industrial Sciences (ENSAI)
Department of Food Science and Nutrition
University of Ngaoundere, PO Box 455, Ngaoundere, Cameroon
E-mail: [email protected]
Received Date: December 28, 2015 Accepted Date: February 24, 2016 Published Date: March 04, 2016
Citation: Edith NF, Elias EL, Carl MFM (2016) Pleurotus florida Aqueous Extracts and Powder Influence Lipid Profile and Suppress Weight Gain in Rats Fed High Cholesterol Diet. J Nutr Food Sci 6:473. doi: 10.4172/2155-9600.1000473
Copyright: © 2016 Edith NF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Pleurotus florida mushroom is a nutritious food with therapeutic potential. This study investigates the effects of P. florida aqueous extracts and powder on serum lipid profile and weight gain in rats fed high cholesterol (HC) diets. Twenty five male albino rats were partitioned into five groups (n = 5): BD: basal diet; HC: High Cholesterol diet; HCPFP5: HC plus 5% P. florida powder; HC-PFE5: HC plus 5% P. florida powder extract; HC-PFE7.5: HC plus 7.5% P. florida powder extract. Animals had free access to diets and water for 4 weeks. Results showed that weight gain was significantly (P < 0.05) suppressed in rats fed high cholesterol diet supplemented with P. florida powder or its extracts, compared to rats fed high cholesterol diet alone. Additionally, supplementation with P. florida increased fecal lipid excretion, while serum triglyceride, LDL, VLDL and total cholesterol decreased. HDL-C increased and LDL-C/HDL-C ratio decreased in rats fed P. florida. These results show that P. florida extracts like powders possess antihypercholesterolemic effects and prevent weight gain, thus reducing the risk for cardiovascular diseases. Mechanisms for these effects are suggested.