alexa Pneumonitis with Nonspecific Interstitial Pneumonia Pattern Caused by Nivolumab in a Patient with Metastatic Melanoma | OMICS International
ISSN: 2165-8048

Internal Medicine: Open Access
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report

Pneumonitis with Nonspecific Interstitial Pneumonia Pattern Caused by Nivolumab in a Patient with Metastatic Melanoma

Kenji Sawa1, Tomoya Kawaguchi1,2*, Shigeki Mitsuoka2, Nao Kusutani3 and Kazuto Hirata1
1Department of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan
2Department of Clinical Oncology, Graduate School of Medicine, Osaka City University, Osaka, Japan
3Department of Dermatology, Graduate School of Medicine, Osaka City University, Osaka, Japan
*Corresponding Author : Tomoya Kawaguchi
Department of Respiratory Medicine
Graduate School of Medicine
Osaka City University
1-4-3 Asahimachi, Abeno-ku
Osaka 545-8585, Japan
Tel: +81-6-6645-3916
Fax: +81-6-6646-6160
E-mail: [email protected]
Received date: March 10, 2016; Accepted date: March 21, 2016, 2016; Published date: March 27, 2016
Citation: Sawa K, Kawaguchi T, Mitsuoka S, Kusutani N, Hirata K (2016) Pneumonitis with Nonspecific Interstitial Pneumonia Pattern Caused by Nivolumab in a Patient with Metastatic Melanoma. Intern Med 6:215. doi:10.4172/2165-8048.1000215
Copyright: © 2016 Sawa K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

A 67-year-old man with metastatic melanoma was treated with nivolumab, which is an antibody against programmed cell death 1 (PD-1). After the 15th course of therapy, he developed drug-induced pneumonitis with a radiologic pattern that was consistent with nonspecific interstitial pneumonia (NSIP). The treatment with glucocorticoid was initiated and his symptoms and radiologic abnormalities rapidly resolved. Early initiation of glucocorticoid can be effective in the treatment of pneumonitis caused by nivolumab. Since increased use of immune checkpoint inhibitors is expected, radiologic and clinical information on pneumonitis caused by anti-PD-1 drugs is required. Here we report our case to provide the detailed radiologic finding of pneumonitis caused by nivolumab and the clinical outcome.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version