Journal of Physical Chemistry & Biophysics
Open Access

Abstract

Nine Insights

Michael Thomas Deans

During a primordial ice age, the ferroelectric phase transition at 72 K in ice crystallised in liquid N2 released latent energy as ~4 μ infrared laser light, ice-light. It photo-phosphorylated deoxynucleotides creating DNA, order amidst chaos. DNA formed tRNA analogues, transport DNAs, tDNAs selectively fed coacervate proto-cells with nutrients promoting anabolic reactions, a replicate tDNA signalled life’s origin. Sub-cellular organelles forming resonant cavities for phosphodiester bond energy released from ATP (replacing ice-light) mediate energy conversions. 189 anti-parallel β-pleated-sheet hairpin protein units with alternate neutral/basic A | L | I | V / K | R residues, P forming 17°C bends between adjacent units, form 21-unit coils and nine coils complete a minion; probably evolved to pack chromosomes for efficient replication, their inter-connecting proton-ordered H-bonds serve as biological clocks and chips-in-thebrain. Apart from substrate transport, tDNAs interact with NAD[PH]’s nicotinamide, protonating gases for nitrogen fixation and oxygenating Earth’s atmosphere. Contrary to Mitchell’s chemiosmotic hypothesis, tDNAs exchanging phospho-mevalonate, residue of saturated fat breakdown, for its lactone actively transports water, Se exchanging Mn++/Ca++ enables Mn to cofactor enzymes converting surplus mevalonate to cholesterol. AI modelled on minions would compensate for personality bias, promising better matchmaking, diplomacy and interdisciplinary discourse. Protons accelerated along minion tunnels have sufficient energy to fuse with obstructing nuclei, harnessing the energy of γ-rays released by the carbon-nitrogen cycle could counter climate change. Nutrient starved DNAs feeding from gastrula or blastula at cell division synthesize hook proteins, their pairing inter-connects tissue cells and enables suppression of tumour and cancer formation.