alexa Polycystic Ovarian Syndrome: Insights into Pathogenesis

Journal of Pharmacological Reports
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Review Article

Polycystic Ovarian Syndrome: Insights into Pathogenesis, Diagnosis, Prognosis, Pharmacological and Non-Pharmacological Treatment

Ahmed M Kabel1,2*
1Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt
2Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi Arabia
Corresponding Author : Ahmed M Kabel
Department of Pharmacology, Faculty of Medicine
Tanta University, Tanta, Egypt, Postal Code 31527
Tel: +201009041488; +966564833526
E-mail: [email protected]
Received December 21, 2015; Accepted January 05, 2016; Published January 08, 2016
Citation: Kabel AM (2016) Polycystic Ovarian Syndrome: Insights into Pathogenesis, Diagnosis, Prognosis, Pharmacological and Non-Pharmacological Treatment. J Pharma Reports 1:103. doi:10.4172/jpr.1000103
Copyright: © 2016 Kabel AM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. Its prevalence may reach up to 18% of women of reproductive age. It usually presents with irregular menstrual cycles, signs of hyper-androgenism and insulin resistance. Patients with PCOS are at increased risk for developing reproductive, metabolic and cardiovascular disorders, including infertility, insulin resistance, diabetes mellitus type 2, hypertension and atherosclerosis. Moreover, it may affect daily physical activities. Management of PCOS aims to lower body weight and insulin levels, restore fertility, treat hirsutism or acne, restore regular menstruation and prevent complications.

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