alexa Polyphenols Nanoencapsulation for Therapeutic Applicati
ISSN: 2167-7956

Journal of Biomolecular Research & Therapeutics
Open Access

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Review Article

Polyphenols Nanoencapsulation for Therapeutic Applications

Conte R1, Calarco A2, Napoletano A2, Valentino A2, Margarucci S2, Di Cristo F2, Di Salle A2* and Peluso G2

1Institute for Polymers, Composites and Biomaterials - National Research Council, Pozzuoli, Italy

2Institute of Bioscience and BioResources - National Research Council, Naples, Italy

*Corresponding Author:
Di Salle A
Institute of Bioscience and Bio Resources
Naples, Italy,
Tel: +39-0816132569
E-mail: [email protected]

Received date: March 09, 2016; Accepted date: April 28, 2016; Published date: May 06, 2016

Citation:Conte R, Calarco A, Napoletano A, Valentino A, Margarucci S, et al.(2016) Polyphenols Nanoencapsulation for Therapeutic Applications. J Biomol Res Ther 5:139. doi:10.4172/2167-7956.1000139

Copyright: © 2016 Conte R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Natural polyphenols are valuable compounds present in plants, fruits, legumes, chocolate, tea, wine and marine organisms possessing scavenging properties towards radical oxygen species. These abilities make polyphenols interesting either for the treatment of various diseases like inflammation and cancer or for anti-ageing purposes in cosmetic formulations. Unfortunately, such compounds lack in long-term stability, are very sensitive to light, and often present a low water solubility and poor bioavailability. To overcome these limitations and enhance polyphenols therapeutic applications, nanotechnology-based delivery systems have been developed, and among all, nanoencapsulation represented a promising strategy. This review described a recent overview of physicochemical nanoencapsulated polyphenols focusing on the most representative molecules such as resveratrol, quercetin, epigallocatechin-3-gallate, and curcumin.


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