Polyvinyl Alcohol in Medicine and Pharmacy: A Perspective
Srinath Muppalaneni and Hossein Omidian*
College of Pharmacy, Nova Southeastern University, Fort Lauderdale, 33328, USA
- *Corresponding Author:
- Hossein Omidian
Associate Professor, College of Pharmacy
Nova Southeastern University, 3200 S University Drive
Fort Lauderdale, FL 33328, USA
E-mail: [email protected]
Received Date: September 30, 2013; Accepted Date: December 20, 2013; Published Date: December 27, 2013
Citation: Muppalaneni S, Omidian H (2013) Polyvinyl Alcohol in Medicine and Pharmacy: A Perspective. J Develop Drugs 2:112. doi: 10.4172/2329-6631.1000112
Copyright: © 2013 Muppalaneni S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Polyvinyl alcohol (PVOH) is a synthetic hydrophilic linear polymer that generally exists as a copolymer of vinyl alcohol and vinyl acetate. Therefore, the structural properties of PVOH polymers primarily depend on the degree of polymerization and the degree of hydrolysis, i.e., the ratio of the two monomers. Due to reactive functional groups on its structure, PVOH undergoes chemical changes such as esterification and etherification, as well as physical changes such as crystallization and ion-polymer complexation. Both chemically and physically-modified PVOH structures have found applications in biomedical and pharmaceutical area. This article reviews the properties of PVOH in solid and solution states, PVOH hydrogels and cryogels, their biomedical and pharmaceutical applications, and their potential challenges.