Population Genetics for Autosomal STR Loci in Sikh Population of Central India
- *Corresponding Author:
- Pankaj Shrivastava
DNA Fingerprinting Unit
State Forensic Science Laboratory
Sagar-470001, Madhya Pradesh, India
Tel: 94243 71946
Email: [email protected]
Received Date: February 4, 2015; Accepted Date: February 23, 2015; Published Date: February 26, 2015
Citation: Dogra D, Shrivastava P, Chaudhary R, Gupta U, Jain T (2015) Population Genetics for Autosomal STR Loci in Sikh Population of
Central India. Hereditary Genet 4:142. doi: 10.4172/2161-1041.1000142
Copyright: ©2015 Dogra D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This study is an attempt to generate genetic database for three endogamous populations of Sikh population (Arora, Jat and Ramgariha) of Central India. The analysis of eight autosomal STR loci (D16S539, D7S820, D13S317, FGA, CSF1PO, D21S11, D18S51, and D2S1338) was done in 140 unrelated Sikh individuals. In all the three studied populations, all loci were in Hardy -Weinberg equilibrium except at locus FGA in Ramgariha Sikh and locus D16S539 in Arora Sikh. An analysis of molecular variance (AMOVA) showed 1% variation among the three studied populations. The close genetic relationship between Jat and Ramgariha Sikh population were confirmed in the MDS Plot generated from the pairwise genetic distances.