Portal Vein Thrombosis: The Overlooked Association between Pancreatic Cancer and PVT
- *Corresponding Author:
- Shreena Dhawan
Medical Student of Surgery
American University of Integrative Sciences
Cole Bay, USA
E-mail: [email protected]
Received Date: January 27, 2017 Accepted Date: March 21, 2017 Published Date: March 26, 2017
Citation: Badi Y, Badro N, Dhawan S (2017) Portal Vein Thrombosis: The Overlooked Association between Pancreatic Cancer and PVT. Oncol Cancer Case Rep 3: 128. doi: 10.4172/2471-8556.1000128
Copyright: © 2017 Badi Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Portal vein thrombosis (PVT) is a complication of prothrombic disorders liver cirrhosis and malignancies. Pancreatic malignancy, specifically, is notorious for this complication because it upregulates tissue factor production, which activates the extrinsic coagulation cascade, thus inducing a hypercoagulable state. In this state, the body is susceptible to thrombus formation, resulting in venous thromboembolism (VTE) or PVT. Thus, considering a pancreatic malignancy as a top differential for PVT must be emphasized.