alexa Posterior Urethral Valves Disorder in Non-Twin Siblings: Case Report and Literature Review
ISSN: 2168-9857

Medical & Surgical Urology
Open Access

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Case Report

Posterior Urethral Valves Disorder in Non-Twin Siblings: Case Report and Literature Review

Lucas Medeiros Burttet1, Tiago Elias Rosito1,2, Gustavo Baldino Nabinger1, Milton Berger1 and Brasil Silva Neto1

1Department of Urology, Hospital de Clínicas de Porto Alegre, Brazil

2Department of Pediatric Urology, Hospital de Clínicas de Porto Alegre, Brazil

*Corresponding Author:
Lucas Medeiros Burttet
Department of Urology, Hospital de Clínicas de Porto Alegre
Rua Ramiro Barcelos, 2350. Bairro Santa Cecília.
Porto Alegre/RS. Brazil. CEP: 90035-003
Tel: +55 51 33598286
Fax: +55 51 33598000
E-mail: [email protected]

Received date : February 14, 2014; Accepted date : March 24, 2014; Published date : March 29, 2014

Citation: Burttet LM, Rosito TE, Nabinger GB, Berger M, Neto BS (2014) Posterior Urethral Valves Disorder in Non-Twin Siblings: Case Report and Literature Review. Med Surg Urol 3:133. doi:10.4172/2168-9857.1000133

Copyright: © 2014 Burttet LM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Although a rare condition, Posterior Urethral Valves (PUVs) are the most common obstructive cause of chronic renal disease in children. In order to provide an early diagnosis, it is crucial to identify families with a high risk of developing this disorder. Here, we report a rare case of non-twin siblings with PUV. The first sibling was diagnosed at 2 months of age, presenting with renal insufficiency and managed properly. Despite the brother’s history and general prenatal care, the second sibling presented with the same disorder, at 3 months of age, suffering from acute renal insufficiency, urinary tract infection and severe anemia, revealing even more important complications than the first sibling. We have reviewed the 12 cases of non-twin siblings previously reported in the literature, and noticed that in the majority of these families, late diagnosis was observed. Herein, we discuss aspects of management of the disorder, and highlight the importance of specific antenatal evaluation in boys with a positive family history.


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