Postmortem Methamphetamine Distribution
Iain M. McIntyre*, Catherine Hamm and Ernie Bader
Director and Chief Toxicologist, San Diego County Medical Examiner's Office, 5570 Overland Ave., CA, USA
- *Corresponding Author:
- Dr. Iain M. McIntyre
San Diego Medical Examiner's Office
5570 Overland Ave., Suite 101 San Diego
CA. 92123, USA
Tel: 858 694 2907
Fax: 858 495 5383
E-mail: [email protected]
Received date: March 19, 2011; Accepted date: April 06, 2011; Published date: April 11, 2011
Citation: McIntyre IM, Hamm C, Bader E (2011) Postmortem Methamphetamine Distribution. J Forensic Res 2:122. doi: 10.4172/2157-7145.1000122
Copyright: © 2011 McIntyre IM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Methamphetamine is a commonly abused central nervous system stimulant. The San Diego County Medical Examiner’s Office has seen increasing positive methamphetamine cases that do not have a suitable blood sample for analysis. We compare liver, vitreous, and central blood levels of methamphetamine and the metabolite amphetamine to levels in peripheral blood samples in 18 medical examiner cases. Specimens were screened by ELISA and confirmed by GCMS analysis following liquid-liquid extraction. Methamphetamine central blood to peripheral blood ratios averaged 1.61 (± 0.48), vitreous to peripheral blood 1.63 (± 0.75) and liver to peripheral blood 5.68 (± 2.32). The data suggests that in cases where blood is not available, vitreous and liver specimens are useful in confirming methamphetamine use.