alexa Potent Role of Antioxidant Molecules in Prevention and
ISSN: 2155-9554

Journal of Clinical & Experimental Dermatology Research
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Review Article

Potent Role of Antioxidant Molecules in Prevention and Management of Skin Cancer

Wahida Khan Chowdhury1, Shahida Arbee2, Sujan Debnath3, Shah Mehedi Bin Zahur4, Sharmim Akter5, A K M Rezaul Karim6, Mohammad Mohabbulla Mohib 7,8, Abida Tisha8, Md Abu Taher Sagor8* and Sharif Mohiuddin2

1Department of Dermatology, Shahabuddin Medical College and Hospital, Bangladesh

2Department of Anatomy and Physiology, Pioneer Dental College and Hospital, Bangladesh

3Department of Dental Public Health, Pioneer Dental College, Bangladesh

4Infectious Disease Division, (icddr,b)s, Bangladesh

5Department of Medicine, Dhaka Central International Medical College and Hospital, Bangladesh

6Department of Pediatric Hematology Oncology, Chittagong Medical College Hospital, Chittagong-4203, Bangladesh

7Research Institute for Medicines (iMed.ULisboa) Faculty of Pharmacy, Universidade de Lisboa, Portugal

8Department of Pharmaceutical Sciences, School of Life Sciences, North South University, Bangladesh

*Corresponding Author:
Md Abu Taher Sagor
Department of Pharmaceutical Sciences
North South University, Dhaka-1229, Bangladesh
Tel: 8801718130130
E-mail: [email protected]

Received date: April 22, 2017; Accepted date: May 09, 2017; Published date: May 15, 2017

Citation: Chowdhury WA, Arbee S, Debnath S, Bin Zahur SM, Akter S, et al. (2017) Potent Role of Antioxidant Molecules in Prevention and Management of Skin Cancer. J Clin Exp Dermatol Res 8:393. doi: 10.4172/2155-9554.1000393

Copyright: © 2017 Chowdhury WK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Evidence reported that cancers are spreading every nook and corner of the world at an alarming rate. Skin diseases like chronic skin inflammations, psoriasis and skin cancers have also been burning topic in today. Protections of a biological system are often hampered while skin gets damaged. Factors like UV, radiation, viruses, chronic diseases, genetic predispositions, food habits and environmental exposures might lead to skin cancers. In addition to these, urbanization and globalization may also contaminate the environment that may eventually modify several biological and genetic functions. USA, Europe and Australia are in the most dangerous zone to be exposed. We basically performed detailed search of PubMed, Google Scholar and Science Direct for literature search and collecting related information. On the other hand, experiments suggested that antioxidant components such as phenolic acid derivatives, flavonoids and flavonol found to be preventive against cancer cell proliferations. Moreover, antioxidants have been also evaluated as a protective agent against chronic inflammatory diseases as well. These molecules may participate as an additional therapy which could exert synergistic effects while applying with other chemotherapeutic agents. Our literature findings and hypothetical figure may establish a good correlation between skin cancer and antioxidant therapy. Therefore this study will be focused on skin cancer biology and some possible management strategies using antioxidant phyto-nutrients.



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