Potential Anti-Microbial, Anti-Inflammatory and Anti-Oxidant Activities of Haplophyllum tuberculatum Growing in LibyaOmar M Sabry1*, Abeer M El Sayed1 and Amany A Slee2
- *Corresponding Author:
- Omar M Sabry
Faculty of Pharmacy, Cairo University
Kasr El-Einy Street, 11562, Cairo, Egypt
Received date: January 09, 2016; Accepted date: February 16, 2016; Published date: February 22, 2016
Citation: Sabry OM, EI Sayed AM, Slee AA (2016) Potential Anti-Microbial, Anti-Inflammatory and Anti-Oxidant Activities of Haplophyllum tuberculatum Growing in Libya. J Pharmacogn Nat Prod 2:116. doi: 10.4172/2472-0992.1000116
Copyright: © 2016 Sabry OM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Ethanolic extract of the aerial parts of Haplophyllum tuberculatum demonstrated an efficient anti-fungal activity against Aspergillus fumigates, Geotricum candidum and Syncephalastrum racemosum with (MIC 0.49, 0.12 and 1.95 μg/ml). It also presented 75% potency as antibacterial agent on Staphylococcus aureus and Escherichia coli (MIC 1.95 and 15.63 μg/ml). Volatile oil of the aerial parts demonstrated significant antibacterial effect against Enterococcus faecalis and Lactobacillus acidophilus (MIC 1.95 and 0.98 μg/ml). The essential oils from aerial parts and flowers exhibited a remarkable acute anti-inflammatory activity against carrageenan induced oedema in rats 9.52 and 8.56 which were found to be comparable to the standard drug at the selected dose. The ethanolic extract of the aerial parts exhibited significance anti-oxidant activity (98%) as compared to vitamin E.