alexa Prediction of Treatment Resistance in Conservative Treatment of Osteoporotic Vertebral Fractures Using Lateral Plain Dynamic Loading Radiographs | OMICS International| Abstract
ISSN: 2165-7939

Journal of Spine
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Research Article   
  • J Spine 2017, Vol 6(6): 404
  • DOI: 10.4172/2165-7939.1000404

Prediction of Treatment Resistance in Conservative Treatment of Osteoporotic Vertebral Fractures Using Lateral Plain Dynamic Loading Radiographs

Toru Funayama1*, Toshinori Tsukanishi2, Tetsuya Abe1, Hiroshi Kumagai1, Shigeo Izawa2, Hiroshi Noguchi1, Kengo Fujii1, Yousuke Shibao1, Masao Koda1 and Masashi Yamazaki1
1Department of Orthopedic Surgery, University of Tsukuba, Tsukuba, Japan
2Department of Orthopedic Surgery, Kenpoku Medical Center, Takahagi Kyodo Hospital, , Japan
*Corresponding Author : Toru Funayama, Department of Orthopedic Surgery, University of Tsukuba, Tsukuba, Japan, Tel: +81-29-853-3219, Fax: +81-29-853-3162, Email: [email protected]

Received Date: Dec 10, 2017 / Accepted Date: Dec 26, 2017 / Published Date: Dec 31, 2017

Abstract

Purpose: To elucidate the association between computed tomography (CT)/magnetic resonance imaging (MRI) and radiographic findings of fractured vertebral body instability in patients with osteoporotic vertebral fractures and to clarify whether resistance to conservative treatment can be evaluated on the basis of dynamic loading radiography.
Methods: Seventy-eight patients aged ≥ 65 years who underwent conservative treatment for osteoporotic single vertebral fractures of the thoracolumbar junction were divided into the conservative treatment-resistant group (18 patients) and control group (60 patients). We evaluated the accuracy of the prediction of resistance to conservative treatment on the basis of the CT/MRI findings and the difference in compression rates between standing and supine positions at the time of the first visit. The differences in compression rates (%) were compared between the two groups. In addition, a receiver operating characteristics (ROC) curve was drawn to evaluate the accuracy of the prediction of resistance to conservative treatment.
Results: In patients without (47 cases) and with CT findings (31 cases), the mean differences in compression rates (%) was 8.9% and 19.1%, respectively (p=0.0029). The mean differences in compression rates (%) of patients without (60 cases) and with MRI findings (18 cases) was 9.7% and 24.0%, respectively (p=0.0043). The mean differences in compression rates (%) in the conservative treatment-resistant group was 26.3%, while that in the control group was 9.0 (p=0.0066). In addition, according to the ROC curve of the difference in compression rate was 0.93 (95% confidence interval: 0.87–1), and when a 20% difference in compression rate was considered as the threshold value.
Conclusion: Dynamic loading radiography is useful for the evaluation of resistance to conservative treatment in patients with osteoporotic vertebral fractures, and that a compression rate difference of ≥ 20% predicts resistance to conservative treatment.

Keywords: Osteoporotic vertebral fracture; Thoracolumbar junction; Conservative therapy; Prediction of treatment resistance; Lateral plain dynamic loading radiograph

Citation: Funayama T, Tsukanishi T, Abe T, Kumagai H, Izawa S, et al. (2017) Prediction of Treatment Resistance in Conservative Treatment of Osteoporotic Vertebral Fractures Using Lateral Plain Dynamic Loading Radiographs. J Spine 6: 404. Doi: 10.4172/2165-7939.1000404

Copyright: © 2017 Funayama T, et al. This is an open-access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Select your language of interest to view the total content in your interested language

Post Your Comment Citation
Share This Article
Article Usage
  • Total views: 1225
  • [From(publication date): 0-2017 - Dec 13, 2019]
  • Breakdown by view type
  • HTML page views: 1170
  • PDF downloads: 55
Top