alexa Prednisone May Improve the Outcomes of Women with Recurrent Pregnancy Loss and Increased Levels of Peripheral Nk Cells: A Real World Clinical Report | OMICS International| Abstract
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
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  • Research Article   
  • J Clin Cell Immunol 2018, Vol 9(6): 571
  • DOI: 10.4172/2155-9899.1000571

Prednisone May Improve the Outcomes of Women with Recurrent Pregnancy Loss and Increased Levels of Peripheral Nk Cells: A Real World Clinical Report

Pierpaolo Di Micco1,2*, Ida Strina2, Roberto Nisini2, Marco Antonio Rigatti3 and Corrado Lodigiani2
1UOC Medicina, Ospedale Fatebenefratelli di Napoli, Italy
2Thrombosis Center, Istituto Clinico Humanitas, Rozzano, Milano, Italy
3Obstetrics and Gynaecological Division, Clinica Sanatrix, Naples, Italy
*Corresponding Author : Pierpaolo Di Micco, UOC Medicina, Ospedale Fatebenefratelli di Napoli, Italy, Email: [email protected]

Received Date: Oct 25, 2018 / Accepted Date: Nov 30, 2018 / Published Date: Dec 10, 2018

Abstract

Recurrent pregnancy loss is a major health problem that may involve nearly 3-5% of women in reproductive age. Several causes of recurrent pregnancy loss are well known and currently investigated and treated in daily practice. Immunological abnormalities are frequently discussed in this clinical setting although not clearly investigated, not only for diagnostics tools but also for a therapeutic support prompt to clinical outcome.

Increased levels of peripheral NK cells is in fact a well-recognized abnormality in women with unexplained recurrent pregnancy loss but studies on its treatment are lacking in the literature. We report a clinical series from our personal database on selected women with increased NK cells and recurrent pregnancy loss treated with low doses of prednisone.

Keywords: NK cells; Age; Infertility

Citation: Di Micco P, Strina I, Nisini R, Rigatti MA, Lodigiani C (2018) Prednisone May Improve the Outcomes of Women with Recurrent Pregnancy Loss and Increased Levels of Peripheral Nk Cells: A Real World Clinical Report. J Clin Cell Immunol 9: 571. Doi: 10.4172/2155-9899.1000571

Copyright: © 2018 Di Micco P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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