Preliminary Evaluation of a Nutraceutical Product Made with Residue of Cocos Nucifera for Use in the Treatment of Obesity
Garduño-Siciliano Leticia*, Nava-Ortega Maria Edith, Ortiz-González Luis Felipe, Ortíz-Moreno Alicia, Sánchez-Pardo Maria Elena and Pérez Pasten-Borja Ricardo
Laboratorio de toxicología de productos naturales, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, México
- *Corresponding Author:
- Garduño-Siciliano L
Unidad Profesional Adolfo López Mateos
A. Wilfrido Massieu Esq. Cda. Miguel Stampa s/n
Tel: + 525518000699
E-mail: [email protected]
Received Date: December 30, 2015 Accepted Date: January 09, 2016 Published Date: February 21, 2016
Citation: Leticia GS, Edith NOM,Felipe OGL, Alicia OM, Elena SPM, et al. (2016) Preliminary Evaluation of a Nutraceutical Product Made with Residue of Cocos Nucifera for Use in the Treatment of Obesity. Transl Med (Sunnyvale) 6:166. doi:10.4172/2161-1025.1000166
Copyright: © 2016 Garduño-Siciliano L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
In recent years, agro-industrial residues of plant or vegetal origin have been shown to be a useful source of fiber and antioxidant components. Both types of elements have beneficial effects on human health. Cocos nucifera is abundant in tropical and subtropical countries, and up to 50% of its fruit is considered non-industrializable residue. There is sufficient previous evidence to think that the use of this residue in the manufacture of nutraceutical products may have beneficial effects on weight gain in obese individuals. Therefore, the present study evaluated the toxicological risk of an extract obtained from C. nucifera residue as well as the effectiveness of a nutraceutical product made with this extract, on weight gain in mice with diet-induced hypercholesterolemia. Our results show reduced weight gain and glucose levels in mice administered the nutraceutical product made with coconut residue extract. This study shows that coconut residue extract is a suitable alternative for obesity control, but further evaluation is needed of other biochemical markers of anti-obesogenic effect to ensure the effectiveness of the nutraceutical product for human consumption.