alexa Preliminary Phytochemical Screening and Antimicrobial Activity of Salvadora persica Linn. Extracts against Oral Pathogens
ISSN: 2165-8056

Fungal Genomics & Biology
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Research Article

Preliminary Phytochemical Screening and Antimicrobial Activity of Salvadora persica Linn. Extracts against Oral Pathogens

Sanjay Kumar1*, Navneet1, Shiv Shanker Gautam1 and Vinod Kumar2
1Department of Botany and Microbiology, Gurukul Kangri University, Haridwar 249404, Uttarakhand, India
2Department of Zoology and Environmental Science, Gurukul Kangri University, Haridwar 249404, Uttarakhand, India
Corresponding Author : Sanjay Kumar
Assistant Professor, Botany and Microbiology
Gurukul Kangri University, Haridwar
Uttarakhand, India
Tel: +919719366637
Email: [email protected]
Received date: Nov 30, 2015; Accepted date: Jan 27, 2016; Published date: Feb 3, 2016
Citation: Kumar S, Navneet, Gautam SS, Kumar V (2016) Preliminary Phytochemical Screening and Antimicrobial Activity of Salvadora persica Linn. Extracts against Oral Pathogens. Fungal Genom Biol 6:131. doi:10.4172/2165-8056.1000131
Copyright: © 2016 Kumar S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Salvadora persica Linn. is used traditionally as hypotensive, emollient, laxative, diuretic, febrifuge, skin cleanser and in treatment of urinary infections, gall stones, bronchial asthma and diarrhoea. The present study was designed for evaluation of phytochemical and anti-microbial aspects of S. persica stem and bark extracts against oral pathogens. The antimicrobial screening of extracts was examined by agar well diffusion method at 200 mg/ml sample concentration and minimum inhibitory concentrations (MICs) by two fold serial dilution method. Ofloxacin was used as positive control to determine the sensitivity of the strains. The results showed that MeOH extract was more active than other extracts in its antimicrobial activity ranged 14.0 ± 0.50-22.3 ± 0.76 mm respectively. MIC values were recorded between 3.12 to 25 mg/ml for all selected pathogens. Phytoconstituents analysis of plant extract revealed the presence of alkaloids, flavonoids, glycosides, steroids, tannins, terpenoids and saponins. The results corroborate the traditional uses of S. persica in treatment of dental diseases.

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