alexa Present and Future RNA-based Approaches to Medical Genomics
ISSN: 2472-128X

Journal of Clinical & Medical Genomics
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Present and Future RNA-based Approaches to Medical Genomics

Robert Penchovsky*

Department of Genetics, Faculty of Biology, Sofia University “St. KlimentOhridski”, 8 Dragan TzankovBlvd., 1164 Sofia, Bulgaria

*Corresponding Author:
Robert Penchovsky
Department of Genetics, Faculty of Biology
Sofia University “St. KlimentOhridski”
8 Dragan TzankovBlvd., 1164 Sofia, Bulgaria
Tel: +35928167340
E-mail: [email protected]

Received date: July 29, 2013; Accepted date: October 08, 2013; Published date: October 18, 2013

Citation: Penchovsky R (2013) Present and Future RNA-based Approaches to Medical Genomics. Int J Genomic Med 1:110. doi: 10.4172/2332-0672.1000110

Copyright: © 2013 Penchovsky R. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Nucleic acids-based technology is emerging as a valuable field that integrates research from science and technology to create novel nanodevices and nanostructures with various applicationsin modern nanotechnology. Nowadays, applicationsof RNA-based technologyare employed in biomedical and pharmaceutical research, biosensoring, nanopharmaceutics and others. It has been proven that RNA isa very suitable medium for selfassembly of diverse nanostructures, catalytic nanodevices and cell delivery systems.At the same time, genomics is becoming increasingly valuable for modern medicine due to the advancements made by second generation sequencing technologies. In this review, I discuss various applications of designer ribozymes and diverse RNAbased approaches to medical genomics. The areas discussed include RNA-based approaches for molecular sensoring and diagnostics, antibacterial drug discovery, exogenous control of gene expression, and gene silencing. These approaches havebecomepossible due to the advancement of various methods for engineering functional RNAsas well asthe discoveries made in RNA biology. Furthermore, different RNA-based antisense technologies are reviewed together with methods for nucleic acid delivery to the cell. The research that has been done so far in the field of RNA engineering hasa far-reaching impact on medical genomics, which isthe main focus of this review.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords