Prevalence and Determinants of Peripheral Neuropathy in Patients with Type 2 Diabetes Attending a Tertiary Care Center in the United Arab EmiratesJuma M Al-Kaabi1, Fatma Al Maskari2*, Taoufik Zoubeidi3, Abdishakur Abdulle1, Syed M Shah2, Paul Cragg4, Bachar Afandi4 and Abdul-Kader Souid5
- *Corresponding Author:
- Fatma Al-Maskari
Institute of Public Health
Director of Zayed Bin Sultan Center for Health Sciences
College of Medicine and Health Sciences
UAE University, PO Box 17666, AL AIN, United Arab Emirates
E-mail: [email protected]
Received date: February 23, 2014; Accepted date: March 24, 2014; Published date: March 28, 2014
Citation: Al-Kaabi JM, Maskari FAl, Zoubeidi T, Abdulle A, Shah SM, et al. (2014) Prevalence and Determinants of Peripheral Neuropathy in Patients with Type 2 Diabetes Attending a Tertiary Care Center in the United Arab Emirates. J Diabetes Metab 5:346 doi: 10.4172/2155-6156.1000346
Copyright: © 2014 Al-Kaabi JM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Methods: Adults with type 2 diabetes mellitus (394 patients, age = 57 ± 12 yr, 67% females, duration of diabetes = 10.9 ± 7.9 yr) were randomly selected from the Diabetes Center at Tawam Hospital (Al Ain City, United Arab Emirates). The Michigan Neuropathy Screening Instrument (MNSI) history and sign scores were used to assess neuropathy. Stepwise logistic regression analysis was used to assess independent predictors of peripheral neuropathy on the Michigan score.
Results: Prevalence of peripheral neuropathy was 10.4% based on the MNSI-history score of ≥7 and 25.6% based on the MNSI-sign score of ≥ 3. Logistic regression analysis revealed that HbA1c [OR=3.41, 95% CI; 1.15– 10.16] and physical activity [OR=4.99, 95% CI; 2.21–11.29] were significant predictors of the MNSI-history score. Age [OR=1.06, 95% CI; 1.03–1.09], height [OR=1.06, 95% CI; 1.02–1.10], systolic blood pressure [OR=1.03, 95% CI; 1.01–1.06] and duration of diabetes [OR=1.08, 95% CI; 1.04–1.13] were significant predictors of the MNSI-sign score.
Conclusion: Peripheral neuropathy was common in the studied diabetic patients and was associated with modifiable risk factors, such as glycemic control, blood pressure control and physical activity.