alexa Prevalence and Determinants of Peripheral Neuropathy in
ISSN: 2155-6156

Journal of Diabetes & Metabolism
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Research Article

Prevalence and Determinants of Peripheral Neuropathy in Patients with Type 2 Diabetes Attending a Tertiary Care Center in the United Arab Emirates

Juma M Al-Kaabi1, Fatma Al Maskari2*, Taoufik Zoubeidi3, Abdishakur Abdulle1, Syed M Shah2, Paul Cragg4, Bachar Afandi4 and Abdul-Kader Souid5

1 Departments of Internal Medicine, College of Medicine and Health Sciences; UAE University, UAE

2 Institute of Public Health, College of Medicine and Health Sciences; UAE University, UAE

3 Department of Statistics, College of Business and Economics, UAE University, UAE

4 Diabetes Center, Tawam-Jones Hopkins Hospital, UAE

5 Department of Pediatrics, College of Medicine and Health Sciences; UAE University, UAE

*Corresponding Author:
Fatma Al-Maskari
Institute of Public Health
Director of Zayed Bin Sultan Center for Health Sciences
College of Medicine and Health Sciences
UAE University, PO Box 17666, AL AIN, United Arab Emirates
Tel: 0097137137452
Fax: 0097137672995
E-mail: [email protected]

Received date: February 23, 2014; Accepted date: March 24, 2014; Published date: March 28, 2014

Citation: Al-Kaabi JM, Maskari FAl, Zoubeidi T, Abdulle A, Shah SM, et al. (2014) Prevalence and Determinants of Peripheral Neuropathy in Patients with Type 2 Diabetes Attending a Tertiary Care Center in the United Arab Emirates. J Diabetes Metab 5:346 doi: 10.4172/2155-6156.1000346

Copyright: © 2014 Al-Kaabi JM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Objective: This study was designed to estimate prevalence and identify relevant determinants of peripheral neuropathy in patients >18 years old with type 2 diabetes mellitus of at least 12 months.

Methods: Adults with type 2 diabetes mellitus (394 patients, age = 57 ± 12 yr, 67% females, duration of diabetes = 10.9 ± 7.9 yr) were randomly selected from the Diabetes Center at Tawam Hospital (Al Ain City, United Arab Emirates). The Michigan Neuropathy Screening Instrument (MNSI) history and sign scores were used to assess neuropathy. Stepwise logistic regression analysis was used to assess independent predictors of peripheral neuropathy on the Michigan score.

Results: Prevalence of peripheral neuropathy was 10.4% based on the MNSI-history score of ≥7 and 25.6% based on the MNSI-sign score of ≥ 3. Logistic regression analysis revealed that HbA1c [OR=3.41, 95% CI; 1.15– 10.16] and physical activity [OR=4.99, 95% CI; 2.21–11.29] were significant predictors of the MNSI-history score. Age [OR=1.06, 95% CI; 1.03–1.09], height [OR=1.06, 95% CI; 1.02–1.10], systolic blood pressure [OR=1.03, 95% CI; 1.01–1.06] and duration of diabetes [OR=1.08, 95% CI; 1.04–1.13] were significant predictors of the MNSI-sign score.

Conclusion: Peripheral neuropathy was common in the studied diabetic patients and was associated with modifiable risk factors, such as glycemic control, blood pressure control and physical activity.

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