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ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
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Research Article

Prevalence and Treatment of Iron Deficiency Anemia in Patients with Chronic Heart Failure

Mansour Rafie1, Hooman Rahmani1, Mahmood Sadr1, Mohammad Forat2, Zahra Behnamfar1, Mohammad Hossein Ahmadieh1 and Reza Rafie3*
1Department of Medicine, Cardiovascular division, Yazd University, Yazd, Iran
2Department of Medicine, Hematology division, Yazd University, Tehran, Iran
3Department of Medicine, University of Southern California, Los Angeles, California, USA
Corresponding Author : Reza Rafie, M.D
1510, San Pablo Street, University of Southern California
Los Angeles, CA 90033, USA
Tel: (310) 871 8782
E-mail: [email protected]
Received June 11, 2012; Accepted July 12, 2012; Published July 18, 2012
Citation: Rafie M, Rahmani H, Sadr M, Forat M, Behnamfar Z, et al. (2012) Prevalence and Treatment of Iron Deficiency Anemia in Patients with Chronic Heart Failure. J Clin Exp Cardiolog 3:205. doi:10.4172/2155-9880.1000205
Copyright: © 2012 Rafie M, et al . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Objective: Approximately 30% of patients with Chronic Heart Failure (CHF) develop anemia. Previous studies showed the beneficial effect of treating the underlying anemia in CHF patients but controversy on the subject remains. We studied the prevalence and treatment of underlying anemia in patients with CHF. Methods and Results: Patients were categorized into three groups: normal hemoglobin levels, anemia of chronic disease; and iron deficiency anemia (IDA). All patients were treated for heart failure. Patients with IDA were treated with iron sulfate. We compared the ejection fractions (EF) and functional capacities both before and after treatment. The prevalence of IDA in our patients was 10.7% and 25.7% of patients had anemia of chronic disease. The mortality rate in the anemic group was 4.9 times higher than the mortality rate in the normal hemoglobin group. Following treatment, there was a significant increase in hemoglobin levels that was more prominent in the IDA group. EF increased in all groups following treatment, but the increase was greatest in the IDA group. Conclusions: Our results demonstrate the improved quality of life that results from treating IDA as part of CHF patient management. Early diagnosis and treatment of anemia can improve EF in patients with CHF.

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