alexa Prevalence and Trends of Hepatitis B, Hepatitis C and Human Immunodeficiency Viruses among Blood Donors in Islamabad, Pakistan 2005-2013 | OMICS International | Abstract
ISSN: 2155-9864

Journal of Blood Disorders & Transfusion
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Research Article

Prevalence and Trends of Hepatitis B, Hepatitis C and Human Immunodeficiency Viruses among Blood Donors in Islamabad, Pakistan 2005-2013

Hasan Abbas Zaheer1*, Umar Saeed2, Yasir Waheed2, Saira Karimi3 and Usman Waheed1

1Safe Blood Transfusion Programme, Government of Pakistan, Blood Transfusion Services, Pakistan Institute of Medical Sciences, Islamabad, Pakistan

2Atta-ur-Rahman School of Applied BioSciences (ASAB), National University of Sciences and Technology (NUST), Pakistan

3Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

*Corresponding Author:
Hasan Abbas Zaheer
Blood Transfusion Services
Pakistan Institute of Medical Sciences, Islamabad, Pakistan
Tel: 0092 333 512 38 14
Fax: 0092 51 926 3238
E-mail: [email protected]

Received date: March 21, 2014; Accepte date:d April 29, 2014; Published date: May 07, 2014

Citation: Zaheer HA, Saeed U, Waheed Y, Karimi S, Waheed U (2014) Prevalence and Trends of Hepatitis B, Hepatitis C and Human Immunodeficiency Viruses among Blood Donors in Islamabad, Pakistan 2005-2013. J Blood Disord Transfus 5:217. doi: 10.4172/2155-9864.1000217

Copyright: © 2014 Zaheer HA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background: Pakistan is a developing country of 190 million people with increased burden of infectious diseases. Hepatitis B virus (HBV), Hepatitis C virus (HCV) and Human Immunodeficiency virus (HIV) are the most important agents responsible for transfusion transmitted viral infections. Blood donors are considered as the healthiest population of a community and screening of HBV, HCV & HIV in blood donors will reflect the true prevalence of these infections in a population.

Material and Methods: The study was conducted from July 2005 to July 2013 at Pakistan Institute of Medical Sciences (PIMS) hospital, Islamabad, Pakistan. 160,376 blood donors from the age 18 years to 60 years were enrolled in this study. Study was approved by the ethical review committee of PIMS hospital. All the samples were screened for Hepatitis B virus surface Antigen (HBsAg), anti-HCV and anti-HIV by fourth generation ELISA. Statistical analyses were carried out by using SPS software version 17.

Results: Among 160,376 donors, 157,920 (98.47%) were replacement donors. The overall seroprevalence of (HBVsAg), anti-HCV and anti-HIV among blood donors were 2.35%, 3.26% & 0.017% respectively. The prevalence of HBV and HCV co-infection was 0.084%.

Conclusion: The prevalence of Hepatitis B, Hepatitis C and Human Immunodeficiency viruses are high in blood donors and should not be acceptable. There is a need to educate masses to increase the number of voluntary donors to meet the country’s requirement of blood donation


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