Prevalence of High-Risk Underlying Conditions for Pneumococcal Disease Among People Over 50 Years in Catalonia, SpainAngel Vila-Corcoles1,2*, Imma Hospital1, Olga Ochoa-Gondar1,2, Cinta de Diego1, Eva Satue1, Maria Aragon3
- *Corresponding Author:
- Angel Vila Corcoles
Primary Health Care Service
“Camp de Tarragona”
Institut Catala de la Salut
E-mail: [email protected]
Received Date: July 14, 2016; Accepted Date: August 04, 2016; Published Date: August 11, 2016
Citation: Vila-Corcoles A, Hospital I, Ochoa-Gondar O, de Diego C, Satue E, et al. (2016) Prevalence of High-Risk Underlying Conditions for Pneumococcal Disease Among People Over 50 Years in Catalonia, Spain. Primary Health Care 6:234.doi:10.4172/2167-1079.1000234
Copyright: © 2016 Vila-Corcoles A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Published data on the frequency and distribution of high-risk factors for pneumococcal disease are limited. This study investigated the prevalence of high-risk underlying conditions for pneumococcal disease among people over 50 years in Catalonia, Spain. Methods: Cross-sectional population-based study including 2,033,465 individuals aged 50 years or older registered at 01/01/2015 in the Catalonian Health Institute. A previously validated institutional research clinical Database was used to identify high-risk conditions to suffer pneumococcal disease (functional or anatomic asplenia, cochlear implants, cerebrospinal fluid [CSF] leaks and/or immunocompromising conditions). Prevalence of risk conditions was compared according to gender and age strata. Results: Of the total 2,033,465 study population, an amount of 176,600 persons (8.7%) had any high-risk condition. Prevalence of high-risk subjects did not substantially differ by gender (9.2% in men vs. 8.2% in women; p<0.001), but considerably increased with increasing age (5.1% in 50-64 years vs. 10.6% in 65-79 years vs. 16.1% in people 80 years or older; p<0.001). Overall, 294 individuals (<0.1%) had anatomical or functional asplenia, 76 (<0.1%) cochlear implants, 41 (<0.1%) CSF leaks, 3,854 (0.2%) had immunodeficiency/AIDS, 16,815 (0.8%) had severe renal disease (nephrotic syndrome or renal failure), 5,034 (0.2%) had received bone marrow transplantation, 103,948 (5.1%) had recent cancer (diagnosed within 5 prior years) and 72,040 (3.5%) received immunosuppressive medication/radiotherapy. Conclusion: In our setting, almost ten percent of people over 50 years have any high-risk factor for pneumococcal vaccination, basically immunocompromising conditions.