alexa Prevention of Type I Diabetes Mellitus: The Role of Imm
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
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Review Article

Prevention of Type I Diabetes Mellitus: The Role of Immune Interventions

Ngugi M Piero1*, Njagi J Murugi2, Oduor R Okoth1, Mgutu A Jalemba1, Ngeranwa NJ Joseph1 and Njagi EN Mwaniki1
1Department of Biochemistry and Biotechnology, Kenyatta University, P.O Box 43844-00100, Nairobi, Kenya
2Department of Environmental Health, Kenyatta University, P.O Box 43844-00100, Nairobi, Kenya
Corresponding Author : Ngugi M. Piero
Department of Biochemistry and Biotechnology
Kenyatta University, P.O Box 43844-00100, Nairobi, Kenya
Tel: +254 20 810901/811278 Ext. 57456, +254 710 349 485/+254 732 264 557
Fax: +254 20 8711575
E-mail: [email protected]
Received: May 10, 2012; Accepted: October 18, 2012; Published: October 25, 2012
Citation: Piero NM, Murugi NJ, Okoth OR, Jalemba MA, Joseph NNJ, et al. (2012) Prevention of Type I Diabetes Mellitus: The Role of Immune Interventions. J Clin Cell Immunol S2:005. doi:10.4172/2155-9899.S2-005
Copyright: © 2012 Piero NM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Diabetes mellitus is a disease of antiquity with an estimated 20,000 people dying prematurely per year due to diabetes associated disease. Type 1 diabetes results from autoimmune destruction of insulin-producing pancreatic cells. Much effort has been dedicated to figure out the autoimmune background of this disease with a view to exploring how the immune system can be manipulated to prevent its occurrence. In this review, we explore the autoimmune basis of type I diabetes mellitus and equally the immune interventions that have been and are being employed to prevent type I diabetes mellitus.

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