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ISSN: 2329-8731

Journal of Infectious Diseases & Preventive Medicine
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Research Article

Previous Treatment Failure or Default Increased the Risk of Massive Hemoptysis in PTB Patients

Xi Liu, Li Ding* and Jinyu Xia

Department of Infectious Diseases, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China

*Corresponding Author:
Li Ding
Department of Infectious Diseases
The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China
Tel: +8613926921192
Email: [email protected]

Received date: February 23, 2017; Accepted date: April 10, 2017; Published date: April 17, 2017

Citation: Liu X, Ding L, Xia J (2017) Previous Treatment Failure or Default Increased the Risk of Massive Hemoptysis in PTB Patients. J Infect Dis Preve Med 5:161. doi:10.4172/2329-8731.1000161

Copyright: © 2017 Liu X, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Hemotysis is one of the hallmark symptoms in pulmonary tuberculosis (PTB), which always causes great anxiety and rarely ignored by the patient. Massive hemoptysis is one of the major causes of death in PTB patients.

Objectives: To evaluate the independent association of risk factors with the occurrence of massive hemoptysis in PTB patients.

Methods: Observational retrospective study of PTB patients with hemoptysis hospitalized in the fifth affiliated hospital of Sun Yat-sen University. Patients were categorized into subjects with massive hemoptysis and with mildmoderate hemoptysis. Independent associations of variables with massive hemoptysis were estimated using univariate analysis.

Results: Of 168 subjects with PTB with hemoptysis, 76 (45.23%) reported the presence of massive hemoptysis. In univariate analysis, retreatment cases were more likely to present massive hemoptysis (P=0.020), especially those who had failed or defaulted treatment (P=0.029). Between the two groups, no significant differences were found in the distribution of demographic characteristics and poor radiographic presentations. There were no significant differences in co-morbid diabetes mellitus (DM), lung infection, or bronchiectasis.

Conclusions: Previous treatment failure or default is an independent risk factor for massive hemoptysis in PTB. Poor radiographic presentations could not predict the occurrence of massive hemoptysis.

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